Japanese Actor And Oscar Nominee Ken Watanabe
The Japanese actor Ken Watanabe fought leukemia in 1989, and though he was successful in defeating the blood cancer, he contracted hepatitis C from a blood transfusion he received during that time. Routine screening of the blood supply for hepatitis C didn’t begin until 1992, and Watanabe was among the many people who contracted the hepatitis C virus from blood products or organ donations before then. That’s one reason that hepatitis C screening is recommended for everyone born between 1945 and 1965 the baby boom generation as the virus was unwittingly being spread through the blood supply in the ’60s, ’70s, and ’80s. Watanabe began hepatitis C treatment in 2005, according to TV Guide.
Will A Person Who Has Hepatitis C Ultimately Need A Liver Transplant
Undiagnosed and untreated hepatitis C can damage the liver to the point where a person could need a transplant. Not every person will develop advanced disease from hepatitis C.
But because we cant always predict what will happen over time, the safest course for most people is to modify anything that can injure the liver before they have advanced disease. This includes curing the virus before there is extensive disease.
Wikipedia: Featured List Candidates/list Of People With Hepatitis C
- The following is an archived discussion of a featured list nomination. Please do not modify it. Subsequent comments should be made on the article’s talk page or in Wikipedia talk:Featured list candidates. No further edits should be made to this page.
The list was promoted by User:Scorpion0422 16:20, 4 November 2008 .
I’m resubmitting this list for FL consideration because I feel it deserves the promotion. I feel that the main reason it failed in its previous nomination was that it simply didn’t get enough support, in spite of the fact that most of the issues raised by reviewers were addressed. I also feel that another reason it didn’t pass was because of the stigma attached to hepatitis C. It’s a short list because of this stigma not many celebrities seem to want to admit publicly that they have the disease. Hepatitis C, in spite of its prevalence , is also difficult to diagnose most people who have it don’t know, so it goes unreported and thus, untreated. This kind of list goes far in alleviating this stigma, and encourages people to get tested, so it has great educational value. —Figureskatingfan 05:14, 24 October 2008 Reply
Sincerely, PeachStatePam PeachStatePam 06:19, 24 October 2008 Reply
- So it took a little while. In addition to adding the line as described above, I have now added a tag that, as Blue Salo suggested, enumerating the criteria for inclusion. —Figureskatingfan 22:56, 26 October 2008 Reply
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Can Hepatitis C Be Cured
Yes, you are considered cured if the hepatitis C virus is not detected when measured with a blood test three months after youve completed treatment. This is called a sustained virologic response and data suggest that you will stay virus free indefinitely. And with newer drugs coming to market, cure rates of up to 90% have been seen in patients with hepatitis C.
Even more important sustained virologic response has been associated with lower rates of liver cancer, cirrhosis and all-cause mortality. This means that getting rid of hepatitis C allows individuals to live longer lives.
How Will My Provider Monitor Me During The Treatment
Your provider will meet with you during treatment to review how well you are tolerating treatment and review laboratory results. Laboratory tests help keep tabs on your health, track the viral load, and determine your response to treatment. You will be given specific dates to go get your blood tested at the lab during and after the treatment.
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Other Side Effects Of Ribavirin
Other side effects of ribavirin may include:
- nausea and vomiting
All DAAs are oral drugs that you swallow. Follow your doctors or pharmacists instructions on how to take these medications. They can also tell you what side effects are possible and symptoms of any serious side effects to look out for.
Celebrities With Hepatitis C
Chronic hepatitis C affects over 3 million people in the United States alone. Celebrities are no exception.
This potentially life threatening virus infects the liver. The virus is transmitted in the blood and can be passed from one person to another.
Some common ways people get the virus are through blood transfusions, injecting drugs, tattooing, and piercing. Many of those infected with hepatitis C dont know how they got it.
A major concern for people with hepatitis C is liver damage. Over time hepatitis C can can cause liver inflammation and swelling, and that may lead to cirrhosis.
Sometimes, the immune system can ward off the hepatitis C virus on its own. There are also various antiviral medications that can cure hepatitis C.
If you have hepatitis C, leading a healthy lifestyle and maintaining a comfortable weight through diet and exercise can greatly help your body heal.
Read on to see how these celebs have managed their hepatitis C diagnosis.
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What Are The Symptoms Of Hepatitis C
Symptoms of Acute Hepatitis C Infection
The majority of newly-infected patients identified with HCV do not have symptoms. The minority of patients who have symptoms typically have complaints of
How do protease inhibitors work?
Protease Inhibitors are termed direct-acting antiviral agents . They directly act on the virus by inhibiting certain enzymes and proteins necessary for replication of the HCV virus.
How do nucleotide polymerase inhibitors work?
Nucleotide analog polymerase inhibitors are another type of direct-acting antiviral agents . They block the action of proteins that HCV uses for making new viruses.
How do NS5A inhibitors work?
These are direct-acting antivirals that block the action the HCV NS5A protein and interfere with making new viruses.
Who should not use these medications?
The contraindications, warnings, and precautions for ribavirin apply when ribavirin is combined with these agents.
- Zepatier, Viekira Pak, and Technivie should not be used by people with moderate to severe liver disease.
- Harvoni is indicated for people with moderate to severe cirrhosis, including those who have received liver transplants.
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Chronic Hepatitis C Infection
Approximately 25% of those with HCV will spontaneously clear the virus within 6 months. However, in most cases , the infection will become chronic. Chronic hepatitis C is often asymptomatic.
Some individuals with chronic hepatitis C infection experience:
Fluctuating alanine aminotransferase levels are characteristic. In addition, thrombocytopenia may be an indication of cirrhosis. Thrombocytopenia is known to increase with the severity of liver disease.
The late sequelae of chronic hepatitis C infection include:
- liver fibrosis or cirrhosis
- hepatocellular carcinoma
Cirrhosis and hepatocellular carcinoma may develop over a period of 20 to 30 years depending on factors such as sex, age, and level of alcohol consumption. Approximately 1% to 5% of individuals with chronic hepatitis C infection will develop hepatocellular carcinoma.
If cirrhosis develops, individuals may experience:
The diagnosis of hepatitis C requires 2 types of tests:
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What Health Professionals Need To Know About Hepatitis C
Hepatitis C is not a vaccine-preventable disease.
Hepatitis C is reportable by laboratories and clinicians to local public health authorities in all provinces and territories.
In Canada:
- hepatitis C antibody and nucleic acid amplification testing methods for screening the blood supply were implemented in 1992
- prior to this implementation, thousands were infected with the hepatitis C virus after receiving blood or blood products
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Who Should Get Tested
Since universal screening of blood and blood products did not occur until 1992, anyone who had a blood transfusion or organ transplant before that time should be tested. It is recommended that people be tested for hepatitis C if they were/are:
- Born between 1945 and 1965
- Exposed to blood and body fluids
- Sharing toothbrushes, razors, nail clippers or other personal items with an infected individual
- Using and/or sharing needles to inject drugs
- Receiving tattoos and body piercings with unsterile needles
- Women thinking about becoming pregnant
- Born to an infected mother
- Receiving long-term hemodialysis
- Having unprotected sex with multiple sex partners or have a history of sexually transmitted diseases
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Protease Inhibitor Antiviral Medications
Protease inhibitors work by preventing the spread of infection within the body by stopping viruses from multiplying.
Grazoprevir is a protease inhibitor for hepatitis C genotypes 1 and 4. Its only available in combination with elbasvir and sold as grazoprevir/elbasvir.
The drug combination is sold under the brand name Zepatier.
List Of People With Hepatitis C
The infectious disease hepatitis C is caused by the hepatitis C virus , which affects the liver. During the initial infection, people often have mild or no symptoms, and there is typically no symptoms early during chronic infection. This condition can progress to scarring of the liver , and advanced scarring . Over many years however, it often leads to liver disease and occasionally cirrhosis. In some cases, those with cirrhosis will develop complications such as liver failure, liver cancer, or dilated blood vessels in the esophagus and stomach.
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Ombitasvir Paritaprevir And Ritonavir Tablets Co
This is a relatively new group of medications to treat genotype 1 hepatitis.
Facts about the drug pack include:
- Treatment time is 12 or 24 weeks.
- Dosage is a pack of tablets containing 12.5 mg of ombitasvir, 75 mg of paritaprevir, and 50 mg of ritonavir, once daily. One 250 mg tablet of dasabuvir is taken twice daily with a meal.
- Common side effects of this group of drugs include nausea, itching, and trouble sleeping. If the person takes ribavirin, side effects include tiredness, nausea, fatigue, and skin reactions.
The following medications may be effective for genotype 2.
What Are The Symptoms
People with newly acquired HCV infection usually are asymptomatic or have mild symptoms. Yellowing of skin might occur in 20%30% of persons, and nonspecific symptoms might be present in 10%20% of persons. It can take many years from the time a person is infected with the virus before symptoms like extreme fatigue, cirrhosis of the liver, liver cancer or liver failure occur.
Out of 100 adults infected with hepatitis C
75-80 develop chronic hepatitis C
60-70 develop chronic liver disease
5-20 develop cirrhosis
1-5 die from liver disease or cancer
If youve tested positive for hepatitis C or think you are at risk, seek care right away to help prevent these complications.
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What About Patients With Hepatitis C Who Also Have Hepatitis B
Hepatitis B virus can flare in patients who are co-infected with hepatitis B and hepatitis C and are taking medication for hepatitis C. This has been reported as a potential risk for patients who are taking hepatitis C treatment and have underlying hepatitis B as well. The flare usually occurs within a few weeks after the patient starts taking medication for hepatitis C. Therefore, patients who have both hepatitis B and hepatitis C should be seen by a hepatitis expertbeforestarting treatment of the hepatitis C they may need to start taking hepatitis B treatment to avoid a hepatitis B flare.
Sofosbuvir Velpatasvir And Voxilapresvir
This drug combination is similar to Epclusa but also includes a drug called voxilapresvir.
Facts about Vosevi include:
- Treatment time is 12 weeks for people without cirrhosis or compensated cirrhosis .
- Dosage is fixed at 400 mg of sofosbuvir, 100 mg of velpatasvir, and 100 mg of voxilapresvir once per day with food.
- Common side effects include tiredness, a headache, diarrhea, and nausea.
Doctors often recommend Vosevi for people who have had previous treatment for hepatitis C that did not work.
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Treatment For People With Hiv And Hepatitis C Co
In the UK, standards for HIV treatment and care are set and monitored by the British HIV Association , the professional association for HIV doctors and other healthcare professionals. The most recent guidelines on HIV and hepatitis co-infection were produced in 2017 . Experts now agree that treatment recommendations for people with HIV and hepatitis C should be the same as for everyone else with hepatitis C, so your treatment will follow national guidelines for hepatitis C treatment.
Like everyone else living with HIV, people with HIV and hepatitis C co-infection are advised to start antiretroviral treatment soon after being diagnosed with HIV. People with co-infection may particularly benefit from early treatment because having well-controlled HIV and restored immune function reduces the risk of liver disease progression.
Current guidelines recommend that everyone with HIV and HCV co-infection should start hepatitis C treatment with DAAs. Treatment is especially urgent if you have moderate or worse liver fibrosis . But everyone with HIV and hepatitis C co-infection can benefit from early hepatitis C treatment because their liver disease may progress faster than it would in an HIV-negative person. Where there is a waiting list for treatment, people with HIV and hepatitis C co-infection are likely to be prioritised, especially if you have moderate or severe fibrosis.
- abacavir/lamivudine
Who Can Prescribe The New Drugs
A section 85 listing on the Pharmaceutical Benefits Scheme will allow general practitioners, as well as specialists, to prescribe the new treatments. This means that people with hepatitis C will be able to be treated by a general practitioner in the community. However, people with more advanced care needs, such as cirrhosis, may still need to see a specialist.
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The Patient Advocate Foundation
This organization provides copay relief and a directory of national and local resources that can offset some of the financial burden of medical expenses.
Whatever the cost, the benefit to the person to eradicate hepatitis C today and not deal with complications is immense, says Joseph Galati, MD, medical director for the center of liver disease and transplantation at Houston Methodist Hospital.
The average person may not appreciate the savings from preventing somebody from getting liver cancer or a liver transplant or the disability associated with chronic hepatitis C, says Dr. Galati. Whatever the cost for treatment is, its a drop in the bucket when you look years down the line as far as the potential cost of living with hepatitis C.
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Wikipedia: Featured List Candidates/list Of People With Hepatitis C/archive1
- The following is an archived discussion of a featured list nomination. Please do not modify it. Subsequent comments should be made on the article’s talk page or in Wikipedia talk:Featured list candidates. No further edits should be made to this page.
The list was not promoted by User:Matthewedwards 22:00, 30 September 2008 .
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Can You Drink Alcohol If You Have Hepatitis C
Hepatitis is inflammation of the liver. Hepatitis C viral infection causes this inflammation. There are several risk factors for contracting HCV infection due to the hepatitis C virus. One serious risk factor is drinking alcohol with HCV infection. The combination of HCV and alcohol can cause complications, and may result in more severe and serious liver injury including chronic cirrhosis . It also increases your chances of developing liver cancer having an alcohol induced increase in viral replication and rapid mutation of the hep C virus,which creates complications like:
- Greater viral capacity
Hepatitis refers to any cause of liver inflammation, with or without scarring of the liver . It is contagious, and is spread from person-to-person by blood-to-blood contact. Other viral causes of hepatitis include hepatitis A, B, C, and E. Other types of noninfectious causes of hepatitis include:
- Excessive alcohol intake
- Medications such as some prescription medications or even acetaminophen, for example, Tylenol liver damage and drug induced liver disease.
- Bacteria and viruses other than the hepatitis viruses
How are hepatitis A, B, and E spread?
- Transmission of hepatitis A and E: These forms of the virus are acquired from improper hygiene during food or drink preparation by someone whos infected.
- Transmission of hepatitis B: This form is spread by blood-to-blood or sexual contact.
What Can Travelers Do To Prevent Hepatitis C Infection
There is no vaccine to prevent hepatitis C. Although there are treatments for chronic hepatitis, it is better to prevent infection by taking the following steps:
- Dont inject drugs
- Make sure tattoo, piercing, and acupuncture equipment has been sterilized
- Dont share toothbrushes or devices that can break the skin, including needles for tattoos, piercings, and acupuncture
- Make sure medical and dental equipment has been sterilized
- Use latex condoms correctly when having sex, especially with new partners
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How Is Hepatitis C Transmitted
Hepatitis C is transmitted through direct blood-to-blood contact. It can be contracted and spread through blood transfusions , unprotected sex, intravenous drug use with dirty or shared needles, body piercings and tattoos using non-sterile ink and needles, and sharing personal items such as toothbrushes, razors and nail clippers. It is not spread through exposure to sweat, urine or tears or close contact with an infected person who sneezes or coughs.