Role In Aquatic Ecosystems
Viruses are the most abundant biological entity in aquatic environments. There are about ten million of them in a teaspoon of seawater. Most of these viruses are infecting heterotrophic bacteria and infecting cyanobacteria and they are essential to the regulation of saltwater and freshwater ecosystems.Bacteriophages are harmless to plants and animals, and are essential to the regulation of marine and freshwater ecosystems are important mortality agents of , the base of the in aquatic environments. They infect and destroy bacteria in aquatic microbial communities, and are one of the most important mechanisms of and nutrient cycling in marine environments. The organic molecules released from the dead bacterial cells stimulate fresh bacterial and algal growth, in a process known as the . In particular, lysis of bacteria by viruses has been shown to enhance nitrogen cycling and stimulate phytoplankton growth. Viral activity may also affect the , the process whereby is in the deep ocean.
Microorganisms constitute more than 90% of the biomass in the sea. It is estimated that viruses kill approximately 20% of this biomass each day and that there are 10 to 15 times as many viruses in the oceans as there are bacteria and archaea. Viruses are also major agents responsible for the destruction of including ,The number of viruses in the oceans decreases further offshore and deeper into the water, where there are fewer host organisms.
How Can I Prevent Spreading Hepatitis B To Others
If you have hepatitis B, follow the steps above to avoid spreading the infection. Your sex partners should get a hepatitis B test and, if they arent infected, get the hepatitis B vaccine. You can protect others from getting infected by telling your doctor, dentist, and other health care professionals that you have hepatitis B. Dont donate blood or blood products, semen, organs, or tissue.
How Serious Is It
- People can be sick for a few weeks to a few months
- Most recover with no lasting liver damage
- Although very rare, death can occur
- 15%25% of chronically infected people develop chronic liver disease, including cirrhosis, liver failure, or liver cancer
- More than 50% of people who get infected with the hepatitis C virus develop a chronic infection
- 5%-25% of people with chronic hepatitis C develop cirrhosis over 1020 years
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Whats The Difference Between Hepatitis A B And C
Chronic Illness, Hepatitis A, Hepatitis B, Hepatitis C, Hepatology, Liver Health
Youve probably seen stories in the news about hepatitis A outbreaks linked to infected restaurant workers, or how a rising rate of hepatitis C infections is causing increased health care costs.
But you might not know the difference between hepatitis A, B and C, or why you should be concerned about them.
Heres why: Hepatitis, or inflammation of the liver, affects more than 50,000 new people each year and is a leading cause of liver cancer and liver transplants. The Centers for Disease Control and Prevention estimates as many as 6 million people in the U.S. are living with hepatitis.
Having hepatitis can be dangerous and uncomfortable. Symptoms are similar for hepatitis A, B and C and may include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, gray-colored stools, joint pain and jaundice . Even worse, chronic hepatitis often has no symptoms, and people dont know theyre infected until they get very sick.
Michael Fried, MD, director of the UNC Liver Center, explains the difference between the types of hepatitis and how to protect yourself.
How Do Doctors Treat Hepatitis B
Doctors typically dont treat hepatitis B unless it becomes chronic. Doctors may treat chronic hepatitis B with antiviral medicines that attack the virus.
Not everyone with chronic hepatitis B needs treatment. If blood tests show that hepatitis B could be damaging a persons liver, a doctor may prescribe antiviral medicines to lower the chances of liver damage and complications.
Medicines that you take by mouth include
A medicine that doctors can give as a shot is peginterferon alfa-2a .
The length of treatment varies. Hepatitis B medicines may cause side effects. Talk with your doctor about the side effects of treatment. Tell your doctor before taking any other prescription or over-the-counter medicines.
For safety reasons, you also should talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices.
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How Do You Get Hepatitis B
The virus that causes hepatitis B lives in blood, semen, and other fluids in your body. You usually get it by having sex with someone who’s infected.
You also can get it if you:
- Have direct contact with infected blood or the body fluids of someone who’s got the disease, for instance by using the same razor or toothbrush as someone who has hepatitis B, or touching the open sores of somebody who’s infected.
- If you’re pregnant and you’ve got hepatitis B, you could give the disease to your unborn child. If you deliver a baby who’s got it, they need to get treatment in the first 12 hours after birth.
Prevent Infection After Contact With The Virus
If you think you have been in contact with the hepatitis B virus, see your doctor right away. Doctors typically recommend a dose of the hepatitis B vaccine to prevent infection. In some cases, doctors may also recommend a medicine called hepatitis B immune globulin to help prevent infection. You must get the vaccine dose and, if needed, HBIG shortly after coming into contact with the virus, preferably within 24 hours.
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Viral Hepatitis Definition And Overview
Hepatitis means inflammation of the liver. Many illnesses and conditions can cause inflammation of the liver, for example, drugs, alcohol, chemicals, and autoimmune diseases. Many viruses, for example, the virus causing mononucleosis and the cytomegalovirus, can inflame the liver. Most viruses, however, do not attack primarily the liver the liver is just one of several organs that the viruses affect. When most doctors speak of viral hepatitis, they are using the definition that means hepatitis caused by a few specific viruses that primarily attack the liver and are responsible for about half of all human hepatitis. There are several hepatitis viruses they have been named types A, B, C, D, E, F , and G. As our knowledge of hepatitis viruses grows, it is likely that this alphabetical list will become longer. The most common hepatitis viruses are types A, B, and C. Reference to the hepatitis viruses often occurs in an abbreviated form The focus of this article is on these viruses that cause the majority of human viral hepatitis.
Hepatitis viruses replicate primarily in the liver cells. This can cause the liver to be unable to perform its functions. The following is a list of major functions of the liver:
Which Is Worse Hepatitis B Or C
The scary thing about liver conditions like hepatitis is that you may be living with it and not even be aware.
Less than half of the people living with hepatitis B or hepatitis C are diagnosed. If you are one of these people living with an undetected case of hepatitis, you may be at risk for developing liver failure or liver cancer and transmitting the illness to other people.
What are the most common hepatitis infections? Is hepatitis B worse than hepatitis C? How is hepatitis detected and treated? Michael D. Cook, certified physician assistant at Gastroenterology Associates of Southwest Florida answers these questions and can help you understand the risks of hepatitis.
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Enhancing Healthcare Team Outcomes
This article discusses hepatitis, which is a complex disease and requires an interprofessional approach from healthcare providers to tackle it. The article discusses strategies to prevent hepatitis through patient education and vaccination and the importance of closer monitoring for disease progression and complications. These strategies require significant interprofessional communication and care coordination by physicians, including primary care physicians and specialists, nurses, pharmacists, and other health professionals, to enhance patient-centered care. Nursing needs to work closely with the patient to ensure they understand their disease, are compliant with medications and vaccines, and note progress or lack thereof. Pharmacists are crucial to ensuring the proper medications at the correct dose are in the therapy regimen, and that there are no interactions. Any issues noted by any member of the interprofessional healthcare team need to be shared and charted, so everyone operates from the same data. These measures can help improve the outcomes and aid to patient safety and can also help enhance team performance.
How Do You Get Hepatitis A
The main way you get hepatitis A is when you eat or drink something that has the hep A virus in it. A lot of times this happens in a restaurant. If an infected worker there doesn’t wash their hands well after using the bathroom, and then touches food, they could pass the disease to you.
Food or drinks you buy at the supermarket can sometimes cause the disease, too. The ones most likely to get contaminated are:
- Shellfish
- Ice and water
You could catch or spread it if you’re taking care of a baby and you don’t wash your hands after changing their diaper. This can happen, for example, at a day care center.
Another way you can get hep A is when you have sex with someone who has it.
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Cirrhosis Of The Liver
Extensive fibrosis is called cirrhosis. Hepatitis B, hepatitis C, and alcoholic hepatitis can cause cirrhosis as well as fatty liver disease and other liver-related conditions. Cirrhosis-related scarring is often irreversible. In severe cases and without treatment, the best course of action may be a liver transplant.
Hepatitis A Vaccine And Travel
If youâre going to a country where hepatitis A is common and youâve never had the virus or the vaccine, start the vaccination process as soon as you can. It takes 2 to 4 weeks after the first dose for the vaccine to work, but even one shot a few days before you leave will give you some protection.
People who are allergic to something in the vaccine and children younger than 6 months might instead get a shot of immune globulin , which will protect against hepatitis A for up to 2 months.
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How Do You Treat Hepatitis C
When Dr. Fried started treating hepatitis C in 1990, the cure rate was 7 percent. Treatments have evolved since then, leading to a 95 percent cure rate. The treatment course includes taking one to a few pills a day for 12 to 24 weeks, and the medicines have few side effects. Hepatitis C is the only chronic viral infection that you can routinely cure, thanks to these new medicines.
Treatment Of Acute Viral Hepatitis
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Supportive care
For most people with acute viral hepatitis, special treatment is not necessary. However, people with severe acute hepatitis may require hospitalization so that symptoms can be treated. If doctors suspect that fulminant hepatitis is developing, the person is hospitalized so that mental status can be monitored, liver tests can be done, and doctors can determine whether liver transplantation is needed.
After the first several days, appetite usually returns and people do not need to stay in bed. Severe restrictions of diet or activity are unnecessary, and vitamin supplements are not required. Most people can safely return to work after the jaundice clears, even if their liver test results are not quite normal.
People with hepatitis should not drink alcohol until they have fully recovered.
The infected liver may not process drugs normally. So a doctor may need to stop a drug or reduce the dosage of a drug that could accumulate to harmful levels in the body . Thus, people with hepatitis should tell their doctor all the drugs they are taking , so that the dosage of the drug can be adjusted if necessary.
If itching occurs, cholestyramine, taken by mouth, is often effective.
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How Do You Get Hepatitis C
Just like hepatitis B, you can get this type by sharing needles or having contact with infected blood. You can also catch it by having sex with somebody who’s infected, but that’s less common.
If you had a blood transfusion before new screening rules were put in place in 1992, you are at risk for hepatitis C. If not, the blood used in transfusions today is safe. It gets checked beforehand to make sure it’s free of the virus that causes hepatitis B and C.
It’s rare, but if you’re pregnant and have the disease, it’s possible to pass it to your newborn.
There are some myths out there about how you get hepatitis C, so let’s set the record straight. It’s not spread by food and water . And you canât spread it by doing any of these things:
- Joint pain
See your doctor as soon as possible if you have any of these symptoms.
Sometimes, people have no symptoms. To be sure you have hepatitis, youâll need to get tested.
What Are The Risk Factors
Some people are at an increased risk for contracting HAV, including:
- people traveling to areas of the world where hepatitis A is common
- men who have sex with men
- people who use injectable or noninjectable drugs
- caregivers for those who have hepatitis A
- people who are experiencing homelessness
- people living with a child whos been adopted from an area where hepatitis A is common
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Deterrence And Patient Education
Patient education is key to preventing and controlling hepatitis, especially viral and alcoholic hepatitis. Patients who have viral hepatitis must obtain education educated regarding the importance of routine follow-up and the importance of monitoring the disease progression and development of complications. They should learn about the importance of personal hygiene, including frequent handwashing. People who are traveling to endemic areas should be advised not to drink untreated water or ingest shellfish or raw seafood, and fruits and veritable should always be eaten after being cooked or after being peeled. Patients who have hepatitis A should not handle food for others until they stop shedding the virus. Patients should receive instruction about not sharing any articles, including toothbrushes, razors, or needles that have the potential for contamination with saliva, semen, or blood. All the patients should avoid using hepatotoxic agents, including alcohol and acetaminophen. Patients who are having a disease progression with liver disease should be referred to a gastroenterologist or hepatologist promptly. Patients with features of liver damage that includes liver fibrosis, cirrhosis, hepatocellular carcinoma, and features of portal hypertension should be monitored with routine labs.
Vaccination
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Hepatitis G
What Is The Outlook
Most people with hepatitis A recover without any complications. Once youve had hepatitis A, you cant get it again. Antibodies to the virus will protect you for life.
Some people may be at an increased risk for serious illness from hepatitis A. These include:
- older adults
acute hepatitis B infections in the United States in 2018.
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How To Protect Yourself Against Hepatitis B
Dr. Fried emphasizes that hepatitis B infection can be prevented by avoiding risky behaviors involving sex and drugs and by getting vaccinated. The hepatitis B vaccination is required for infants at birth, and subsequent vaccinations for adults are also important. There are separate vaccines for hepatitis A and B, but there is also a combination A and B vaccine so you can take care of both types at once. In North Carolina, newborn vaccinations have been required since 1994. Anyone born before this year should talk to their health care provider about being vaccinated for hepatitis B.
Searching For A Cause
From the beginning, doctors had warned Liviahs parents that they might never know why her liver had failed in many cases of pediatric hepatitis, clinicians never find a cause, Dr. Peters said.
In Liviahs case, doctors ruled out a variety of common triggers, but blood tests turned up one possible culprit: an adenovirus.
Although there was no sign of the virus in the liver, an adenovirus infection could have triggered an abnormal immune response that then attacked the liver, Dr. Peters said.
It was not a totally satisfying explanation, she conceded. Adenoviruses do not typically lead to liver damage in healthy children, and Liviahs adenovirus levels were low.
The mystery did not faze Liviahs father. I left the hospital going, You know what? Shes alive, he said. I dont really need to know what caused it.
For Mrs. Widders, accepting the unknowns was harder, especially when Liviah had a liver rejection episode that briefly landed her back in the hospital. The setback prompted her mother to wonder whether Liviah might have some kind of genetic or autoimmune disorder, but testing turned up no evidence of that. By the spring, with Liviah home for good, her parents had made peace with the possibility that they might never get answers.
Her daughters liver was slightly inflamed, but her case, like most, turned out to be milder than Liviahs. She was discharged after a few days in the hospital.
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