Signs You Have Hepatitis C

Eat Regular Nutritious Meals

Sometimes people with hepatitis C have a hard time eating. You may have no appetite, feel nauseated, or have different tastes than you are used to. Even if you don’t feel like eating, it’s very important to eat small meals throughout the day. Some people have nausea in the afternoon. If this happens to you, try to eat a big, nutritious meal in the morning.

If you have cirrhosis, it may not be a good idea to eat salty foods or foods that are high in protein. If you want to know more about which foods to avoid and which foods are good to eat, ask your doctor about meeting with a registered dietitian to discuss a healthy eating plan.

What Are The Risk Factors For Hepatitis C

In the United States, having been born between 1945 and 1965, and the use of illicit injection drugs are the two most common factors associated with hepatitis C. Other risk factors include:

• having received blood transfusions prior to 1990,
• hemodialysis, and
• having greater than 10-lifetime sex partners.

Population studies show that hepatitis C is more common among males, non-Hispanic blacks, those with low income, and those with less than a high school education.

People who have HIV/AIDS have an increased risk for hepatitis C, because both these diseases are transmitted in the same ways, through blood and body fluids. If someone has both infections, that person is said to be co-infected with HIV and HCV.

You Notice Unusual Abdominal Pain And Swelling

Most people with liver cancer have pain in the upper right of their abdomen, Dr. Brawley says. Its also often swollen, too. When I examine a patient whos asymptomatic, when I press where their liver is, they say it hurts, he says. Pain in that area does not necessarily indicate liver cancerit could also come from as hepatitis infection, or gallbladder or pancreas problems, he says.

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General Signs And Symptoms Of Hepatitis C

As mentioned, many cases of hepatitis C infection often go unnoticed because they donât always present symptoms. If you do present symptoms, they manifest about four to 12 weeks after initial exposure to the virus. Symptoms can also vary between acute and chronic forms of the infection. Acute hepatitis C symptoms may include:

• Pain in your abdomen
• Fever
• Nausea and/or vomiting

Chronic hepatitis C infections can remain dormant for years, and it usually isnât apparent until the virus has caused significant damage to the liver.

Preventing The Spread Of Hepatitis C

There is no vaccine available to prevent a person from being infected with hepatitis C. Recommended behaviours to prevent the spread of the virus include:

• Always use sterile injecting equipment. This can be accessed from your local needle and syringe program service.
• Avoid sharing personal items such as toothbrushes, razors, nail files or nail scissors, which can draw blood.
• If you are involved in body piercing, tattooing, electrolysis or acupuncture, always ensure that any instrument that pierces the skin is either single use or has been cleaned, disinfected and sterilised since it was last used.
• If you are a healthcare worker, follow standard precautions at all times.
• Wherever possible, wear single-use gloves if you give someone first aid or clean up blood or body fluids.
• Although hepatitis C is not generally considered to be a sexually transmissible infection in Australia, you may wish to consider safe sex practices if blood is going to be present, or if your partner has HIV infection. You may wish to further discuss this issue and personal risks with your doctor.

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Could You Have Hepatitis C And Not Know It

According to recent statistics, African Americans are almost twice as likely to die from a Hepatitis C infection when compared to other ethnicities. This statistic is related to the fact that the viral infection not only has an acute form but a chronic one as well.

To make sure youre not at risk for developing long-term problems from Hepatitis C, you have to learn about the early signs that can be easy to miss.

Typical Symptoms of Hepatitis C

Once youve caught Hepatitis C, youll experience what is known as an acute infection. Unfortunately, the majority of persons have no symptoms at all at this stage. If there are symptoms, they can present themselves anywhere from 2 to 12 weeks after the initial infection and last up to 3 months.

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• Fever
• Muscle aches

The acute stage of the virus is easily treated with medication so there is no need for it to get to the chronic stage.

Of course, a few people with the infection have had the virus pass harmlessly from their systems with no long-term effects.

For others, a chronic infection develops with an even longer list of symptoms. These include:

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Is Liver Transplantation An Option For A Person With Hepatitis C

Hepatitis C is the leading reason for 40% to 45% of liver transplants in the U.S. Hepatitis C usually recurs after transplantation and infects the new liver. Approximately 25% of these patients with recurrent hepatitis will develop cirrhosis within five years of transplantation. Despite this, the five-year survival rate for patients with hepatitis C is similar to that of patients who are transplanted for other types of liver disease.

Most transplant centers delay therapy until recurrent hepatitis C in the transplanted liver is confirmed. Oral, highly effective, direct-acting antivirals have shown encouraging results in patients who have undergone liver transplantation for hepatitis C infection and have recurrent hepatitis C. The choice of therapy needs to be individualized and is rapidly evolving.

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Treatment Of Hepatitis C

Hepatitis C is treated with antiviral medications that aim to clear the virus from your body.

New all-tablet treatments have greatly improved the outcomes for people with hepatitis C. These treatments can cure more than 95% of individuals with chronic hepatitis C. There are several new tablets that are used in combination to treat all hepatitis C strains . They are effective for people with no liver damage and those who have more advanced liver damage or cirrhosis.

These new tablet medications are available and subsidised on the Pharmaceutical Benefits Scheme, and can be prescribed by specialists, general practitioners and specialised nurse practitioners.

There are no restrictions on accessing treatment it is available for all adults with a Medicare card. People under 18 are able to access treatment and it is recommended they are referred to a pediatrician experienced in the treatment of hepatitis C.

For more information on the new medications for the treatment of hepatitis C, see our video: Hepatitis C Cure what it means for Victorians.

If your doctor does not know about the new treatments, you can call the LiverLine on for information, and to find a GP who can help you.

Talk with your doctor about treatment options and the potential for interactions with other medications, herbal preparations and other drugs. If you take prescribed medication this will be managed so you can access treatment.

In general, if you have hepatitis C you will feel better if you:

Tests For The Hepatitis C Virus

If your doctor thinks that you may have hepatitis C, he or she may order:

• A hepatitis C virus test. This is a blood test that looks for antibodies against the hepatitis C virus. It shows whether you have been exposed to the virus.
• A blood test that looks for the genetic material of the hepatitis C virus. This test shows whether you are infected with the virus now.
• A blood test to find out the kind of hepatitis C virus you have. Knowing your genotype will help you and your doctor decide if and how you should be treated.

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Your Eyes Turn Yellow

Yellow eyes are a sign your liver isnt doing very well and is probably the most specific sign of liver disease, says KV Narayanan Menon, MD, medical director of liver transplantation at Cleveland Clinic. A yellow coloured substance called bilirubin is usually broken down by the liver so it can be removed from the body, but when the liver is struggling it can cause bilirubin to build up, leading to yellowing of the whites of the eyes and skin known as jaundice. Jaundice can be caused by a number of health issues, including a viral infection, a blocked bile duct , a reaction to a toxic drug or medicine, liver disease, or conditions that cause an excessive breakdown of red blood cells.

When Should You See A Doctor Or Other Healthcare Professional

Since so many people dont experience any symptoms, healthcare professionals recommend getting screened for hepatitis C at least once in your adult life. They may recommend more frequent screenings if you have a higher risk of contracting the virus.

Hepatitis C doesnt always become severe, but the chronic form can increase your risk for liver damage, liver cancer, and liver failure.

If you have any symptoms that suggest hepatitis C, especially if theres a chance youve been exposed, connect with a doctor or another healthcare professional as soon as possible to discuss your options for testing and treatment.

With a prompt diagnosis, you can get treatment earlier, which may help prevent damage to your liver.

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Youve Had Hepatitis B

Although its unrelated to hepatitis C, hepatitis B can also cause cancer. Canadians get vaccinated as infants or children but others who havent gotten the vaccine could be at risk for liver cancer, Dr. Abou-Alfa says.

Anybody who has hepatitis should have some form of monitoring by a doctor, says Dr. Abou-Alfa. He recommends getting an ultrasound at least once a year to screen for cancer if youve had either virus. Testing for the protein alpha-fetoprotein in the blood could also signal liver cancer, though it hasnt been proven to be an accurate test, Dr. Abou-Alfa says.

What Drugs Treat And Cure Hepatitis C

The treatment of chronic hepatitis C has gone through several generations of medications. Not long ago, treatment was limited to interferon alpha-2b or pegylated interferon alpha-2b , and ribavirin . Interferon and pegylated interferon need to be injected under the skin , while ribavirin is taken by mouth. This combination therapy is infrequently used today, being recommended for only the least common genotypes of hepatitis C virus .

Since 2010, direct-acting antiviral drugs have been in use. The second generation of antivirals for HCV was the protease inhibitors telaprevir and boceprevir , both taken by mouth. These were used in combination with the earlier drugs to increase effectiveness . These drugs are also no longer in common use, and have been replaced by better options.

As more has been learned about how hepatitis C virus multiplies within the liver cells, new drugs continue to be developed to interfere with this multiplication at different stages. As such, we no longer think in terms of generations of drugs, but rather categories of action. Research and development of these direct-acting antivirals continue, with new agents coming to market every few months. Each category is improved and expanded by the addition of new drugs, which are safer and more effective.

Currently available and commonly used direct-acting antiviral drugs include:

• simeprevir

• Muscle aches

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Causes And Risk Factors

HCV causes hepatitis C. People contract the virus through blood-to-blood contact with contaminated blood. For transmission to occur, blood containing HCV must enter the body of a person without HCV.

A speck of blood, invisible to the naked eye, can carry hundreds of hepatitis C virus particles, and the virus is not easy to kill.

The report the following risk factors for developing hepatitis C:

• using or having used injectable drugs, which is currently the most common route in the U.S.
• receiving transfusions or organ transplants before 1992, which is before blood screening became available
• having exposure to a needle stick, which is most common in people who work in healthcare
• being born to a mother who has hepatitis C

The CDC offer advice on cleaning syringes if it is not possible to use clean and sterile ones. Although bleach can kill the HCV in syringes, it may not have the same effect on other equipment. Boiling, burning and using alcohol, peroxide, or other common cleaning fluids to wash equipment can reduce the amount of HCV but might not stop a person from contracting the infection.

It is extremely dangerous to inject bleach, disinfectant, or other cleaning products, so people should make sure they rinse the syringe thoroughly. A person should only ever use bleach to clean equipment if new, sterile syringes and equipment are not available.

People who are at risk due to these factors can have screening to rule out HCV.

• peginterferon alfa-2a
• sofosbuvir

What Are The Treatment Guidelines For Hepatitis C

Hepatitis C treatment is best discussed with a doctor or specialist familiar with current and developing options as this field is changing, and even major guidelines may become outdated quickly.

The latest treatment guidelines by the American Association for the Study of Liver Disease and Infectious Disease Society of America recommends use of DAAs as first-line treatment for hepatitis C infection. The choice of DAA varies by specific virus genotype, and the presence or absence of cirrhosis. In the U.S., specific insurance providers also might influence the choice due to the high cost of DAAs. Although the individual, public health, and cost benefits of treating all patients with hepatitis C is clear, the most difficult barrier to treating all people with HCV is the very high cost of the drug regimens. Patients are encouraged to discuss options with their health care professional.

Treatment is recommended in all patients with chronic hepatitis C unless they have a short life expectancy that is not related to liver disease. Severe life-threatening liver disease may require liver transplantation. Newer therapies with DAAs have allowed more and more patients to be treated.

What are the goals of therapy for hepatitis C infection?

The ultimate goals of antiviral therapy are to

• prevent transmission of hepatitis C,
• prevent progression to cirrhosis and liver cancer, and
• improve survival and quality of life.

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Symptoms Of An Acute Infection

Few people show symptoms during acute infection . These symptoms can include: fatigue tenderness or an aching feeling on the right side of the abdomen decreased appetite perhaps with weight loss flu-like symptoms nausea tendency to bruise or bleed easily jaundice rash dark-coloured urine and light or clay-coloured stools. These symptoms often go away after a short time.

What Other Tests Diagnose Hepatitis C

Once the diagnosis of hepatitis C is established, other tests may be done to determine whether the patient has developed liver fibrosis or scarring . This can be done with a needle biopsy of the liver, and examining the biopsied liver tissue under the microscope. Liver biopsy is less commonly done today because noninvasive tests are more readily available, more easily accomplished and less costly.

Liver imaging can evaluate fibrosis using ultrasound and MRI scans. Additionally, calculations using a variety of blood tests also can predict the degree of inflammation and fibrosis present. Genotype testing will typically be done to determine what subtype of hepatitis C the patient has, as this will impact what drugs are used for treatment.

Testing for other infections including HIV, hepatitis A, and hepatitis B is typically done to determine if the patient might have other conditions that could impact patient’s treatment and prognosis.

With the newest forms of antiviral treatment, the most common types of chronic hepatitis C can be cured in most individuals.

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Hepatitis C Antibody Test

Certain foreign substances that enter your body trigger your immune system to make antibodies. Antibodies are specifically programmed to only target the foreign substance they were made to fight.

If youve ever had a hepatitis C infection, your body will make hepatitis C antibodies as part of its immune response.

Your body only makes these antibodies if you have hepatitis C or had it in the past. So the hepatitis C antibody test can confirm whether you have the virus by testing for these specific antibodies.

It may take 2 to 3 months after exposure for the test to detect antibodies. If needed, your healthcare professional may order an HCV RNA test, which can detect the virus after just 1 or 2 weeks.

If the antibody test is positive, an HCV RNA test can show whether the infection is current.

While people of any gender experience the same hepatitis C symptoms, 2014 research suggested some effects of the virus may differ, depending on the sex you were assigned at birth.

Researchers noted that:

• women have a higher chance of clearing the virus without treatment
• liver disease may progress more rapidly in men
• men have a higher chance of developing cirrhosis

Can You Prevent Hepatitis C Infection

Thereâs no vaccine to prevent hepatitis C. To avoid getting the virus:

• Use a latex condom every time you have sex.
• Don’t share personal items like razors.
• Don’t share needles, syringes, or other equipment when injecting drugs.
• Be careful if you get a tattoo, body piercing, or manicure. The equipment may have someone else’s blood on it.

Find out more on how to prevent hepatitis C.

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