Wednesday, September 21, 2022

What Can Cause Hepatitis C

How Serious Is It

Florida Health Minute: Hepatitis C
  • People can be sick for a few weeks to a few months
  • Most recover with no lasting liver damage
  • Although very rare, death can occur
  • 15%25% of chronically infected people develop chronic liver disease, including cirrhosis, liver failure, or liver cancer
  • More than 50% of people who get infected with the hepatitis C virus develop a chronic infection
  • 5%-25% of people with chronic hepatitis C develop cirrhosis over 1020 years

How Will I Know If My Treatment Works

The goal of treatment is to reduce the amount of the hepatitis C virus in your blood to levels that cant be detected after 24 weeks of therapy. The amount of the virus in your blood is called your viral load. At the end of your treatment, your doctor will need to measure your viral load and find out how healthy your liver is. He or she may repeat many of the same tests that were done when you were first diagnosed with hepatitis C.

If your blood has so few copies of the virus that tests cant measure them, the virus is said to be undetectable. If it stays undetectable for at least 6 months after your treatment is finished, you have what is called a sustained virologic response . People who have an SVR have a good chance of avoiding serious liver problems in the future.

Treatment may not reduce your viral load. You may not have an SVR after treatment. If thats true, your doctor will discuss other treatment options with you. For example, if 1 round of treatment did not decrease your viral load enough, your doctor may recommend a second round. Even if treatment doesnt keep you from having active liver disease, lowering your viral load and controlling chronic liver inflammation may help you feel better for a longer time.

How Can I Protect Myself From Hepatitis C Infection

If you dont have hepatitis C, you can help protect yourself from hepatitis C infection by

  • not sharing drug needles or other drug materials
  • wearing gloves if you have to touch another persons blood or open sores
  • making sure your tattoo artist or body piercer uses sterile tools and unopened ink
  • not sharing personal items such toothbrushes, razors, or nail clippers

Hepatitis C can spread from person to person during sex, but the chances are low. People who have multiple sex partners, have HIV or other sexually transmitted diseases, or who engage in rough or anal sex have a higher chance of getting hepatitis C. Talk with your doctor about your risk of getting hepatitis C through sex and about safe sex practices, such as using a latex or polyurethane condom to help prevent the spread of hepatitis C.

If you had hepatitis C in the past and your body fought off the infection or medicines cured the infection, you can get hepatitis C again. Follow the steps above, and talk with your doctor about how to protect yourself from another hepatitis C infection.

If you think you may have been exposed to the hepatitis C virus, see your doctor as soon as possible. Early diagnosis and treatment can help prevent liver damage.

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How Do Doctors Treat Hepatitis C

Doctors treat hepatitis C with antiviral medicines that attack the virus and can cure the disease in most cases.

Several newer medicines, called direct-acting antiviral medicines, have been approved to treat hepatitis C since 2013. Studies show that these medicines can cure chronic hepatitis C in most people with this disease. These medicines can also cure acute hepatitis C. In some cases, doctors recommend waiting to see if an acute infection becomes chronic before starting treatment.

Your doctor may prescribe one or more of these newer, direct-acting antiviral medicines to treat hepatitis C:

You may need to take medicines for 8 to 24 weeks to cure hepatitis C. Your doctor will prescribe medicines and recommend a length of treatment based on

  • which hepatitis C genotype you have
  • how much liver damage you have
  • whether you have been treated for hepatitis C in the past

Your doctor may order blood tests during and after your treatment. Blood tests can show whether the treatment is working. Hepatitis C medicines cure the infection in most people who complete treatment.

Hepatitis C medicines may cause side effects. Talk with your doctor about the side effects of treatment. Check with your doctor before taking any other prescription or over-the-counter medicines.

For safety reasons, talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices.

What Are The Signs & Symptoms Of Hcv Infection

What You Need to Know About Hepatitis C

Most people with HCV have no symptoms. But even without symptoms, they can develop health problems decades later and can still pass the disease to others.

If symptoms do happen, it’s usually when the disease is very advanced. Symptoms can be similar to those of hepatitis A and hepatitis B and include:

  • jaundice
  • fever
  • darker than usual urine or gray-colored stools

Read Also: How To Know If You Have Hepatitis B

What Is The Treatment For People With Acute Hepatitis C Infection

When people first get hepatitis C, the infection is said to be acute. Most people with acute hepatitis C do not have symptoms so they are not recognized as being infected. However, some have low-grade fever, fatigue or other symptoms that lead to an early diagnosis. Others who become infected and have a known exposure to an infected source, such as a needlestick injury, are monitored closely.

Treatment decisions should be made on a case-by-case basis. Response to treatment is higher in acute hepatitis infection than chronic infection. However, many experts prefer to hold off treatment for 8-12 weeks to see whether the patient naturally eliminates the virus without treatment. Approaches to treatment are evolving. Patients with acute hepatitis C infection should discuss treatment options with a health care professional who is experienced in treating the disease. There is no established treatment regimen at this time.

How effective is hepatitis C treatment? Is hepatitis C curable?

If the hepatitis C RNA remains undetectable at the end of the treatment and follow-up period, this is called a sustained virologic response and is considered a cure. Over 90% of people treated with DAAs are cured. These people have significantly reduced liver inflammation, and liver scarring may even be reversed.

About 5% of people who are treated for HCV infection are not cured by some of the older regimens. These people may still have options for cure with the newer regimens.

Hepatitis C And Liver Cancer: What To Know

Several viruses besides HPV have been linked to cancer, includinghepatitis C, which is linked to liver cancer.

If you think HPV is the only virus that causes cancer, think again. Several other viruses have been linked to cancer, including hepatitis C.

Hepatitis C is the most common blood-borne infection in the United States. Its also the leading cause of liver cancer.

About 30 percent of people who get exposed to the hepatitis C virus will clear it on their own. The rest will go on to have chronic hepatitis C.

This ongoing infection causes inflammation in the liver. This extended inflammation can cause scarring, called cirrhosis, and can ultimately lead to liver cancer.

Chronic hepatitis C also increases the risk of non-Hodgkin lymphoma and head and neck cancers.

Unlike hepatitis A and B, there is no vaccine against hepatitis C, and there are few if any symptoms, says Harrys Torres, M.D., associate professor of Infectious Diseases.

Its a silent infection, he says. And its a very clever virus that mutates very fast, so it has been difficult to develop a vaccine.

Knowing the risk factors and getting screened are your best defenses against cancers caused by hepatitis C. Treatment of this virus can reduce your risk of liver cancer by 75%.

Risk factors

About 75% of those infected with hepatitis C in the United States are baby boomers people born between 1945 and 1965.

Other risk factors for hepatitis C infection include:

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How Is It Spread

Hepatitis A is spread when a person ingests fecal mattereven in microscopic amountsfrom contact with objects, food, or drinks contaminated by feces or stool from an infected person.

Hepatitis B is primarily spread when blood, semen, or certain other body fluids- even in microscopic amounts from a person infected with the hepatitis B virus enters the body of someone who is not infected. The hepatitis B virus can also be transmitted from:

  • Birth to an infected mother
  • Sex with an infected person
  • Sharing equipment that has been contaminated with blood from an infected person, such as needles, syringes, and even medical equipment, such as glucose monitors
  • Sharing personal items such as toothbrushes or razors
  • Poor infection control has resulted in outbreaks in health care facilities

Hepatitis C is spread when blood from a person infected with the Hepatitis C virus even in microscopic amounts enters the body of someone who is not infected. The hepatitis C virus can also be transmitted from:

  • Sharing equipment that has been contaminated with blood from an infected person, such as needles and syringes
  • Receiving a blood transfusion or organ transplant before 1992
  • Poor infection control has resulted in outbreaks in health care facilities
  • Birth to an infected mother

Sharing Toothbrushes Scissors And Razors

Hepatitis C Cure Now Available

There’s a potential risk that hepatitis C may be passed on through sharing items such as toothbrushes, razors and scissors, as they can become contaminated with infected blood.

Equipment used by hairdressers, such as scissors and clippers, can pose a risk if it has been contaminated with infected blood and not sterilised or cleaned between customers. However, most salons operate to high standards, so this risk is low.

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How Does Hepatitis C Affect The Liver

When infected, the liver becomes inflamed, which may cause the healthy, soft tissues in the liver to harden and scar. If not stopped, inflammation and scarring can lead to serious liver diseases such as cirrhosis of the liver or liver tumors. If the damage is severe enough, the liver may not perform all of its functions normally.

Is Screening For Hepatitis C Recommended During Pregnancy

There is a 4%-7% risk of transmitting HCV from mother to infant with each pregnancy. Currently, there is no CDC recommendation for routine hepatitis C screening during pregnancy, and there is no currently recommended medicine to prevent transmission from mother to infant . However, CDC is monitoring research findings and may make recommendations in the future as evidence arises.

While data is still limited, a recent study of over 1,000 cases in the United Kingdom found that 11% of infants had been infected at birth, and that these infants were likely to develop cirrhosis in their early 30s. The case for screening for HCV during pregnancy includes the potential to safely treat mothers during pregnancy with direct-acting antiviral agents to treat the mother before cirrhosis develops, prevent infant transmission, and prevent transmission to others. Children born to HCV-infected mothers may also be offered treatment at an early age to prevent cirrhosis, as well as transmission to others. Coordination of care between multiple specialists will be important to accomplish these goals.

Children of HCV-infected mothers may be screened for hepatitis C as early as 1-2 months of age using hepatitis C viral load or PCR testing . Antibodies to hepatitis C passed from the mother to child will be present for up to 18 months, so children should be tested for HCV antibody no earlier than this.

Also Check: Need For Hepatitis C Screening Test

What Do You Do If You Become Ill

Talk to your health care provider about getting tested if you think you:

If you have hepatitis C, tell those who may have been exposed to your blood or bodily fluids. They should get tested and be treated if necessary. Bodily fluids, like semen and vaginal fluid, are a concern because they could be carrying small amounts of infected blood.

Some adults with hepatitis C will recover from the disease on their own within 6 months. Until your health care provider confirms your recovery status, you are still contagious and can spread the disease.

After recovery, you are no longer contagious because you will not have the disease anymore. But you can get hepatitis C again.

Unfortunately, most adults with hepatitis C:

  • cannot recover on their own
  • develop a more serious form of the disease if they are sick for longer than 6 months

What Is Hepatitis C

Why The Prevention of Hepatitis C is so Important?

Hepatitis C is a liver infection that can lead to serious liver damage. Itâs caused by the hepatitis C virus. About 2.4 million people in the U.S. have the disease. But it causes few symptoms, so most of them don’t know. The virus spreads through an infected personâs blood or body fluids.

There are many forms of the hepatitis C virus, or HCV. The most common in the U.S. is type 1. None is more serious than any other, but they respond differently to treatment.

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How Is Monitoring Done After Treatment For Hepatitis C

Once patients successfully complete treatment, the viral load after treatment determines if there is an SVR or cure. If cure is achieved , no further additional testing is recommended unless the patient has cirrhosis. Those who are not cured will need continued monitoring for progression of liver disease and its complications.

While cure eliminates worsening of fibrosis by hepatitis C, complications may still affect those with cirrhosis. These individuals still need regular screening for liver cancer as well as monitoring for esophageal varices that may bleed.

Because hepatitis B co-infection may reactivate or worsen even after treatment for HCV, monitoring for hepatitis symptoms may be needed after the end of therapy.

Managing Symptoms When Hepatitis Gets Worse

Your doctor will help you manage specific symptoms like itchy skin or pain. You can also make lifestyle changes that can help you feel better and might stop further damage to your liver.

Eat a balanced diet. No matter how advanced your cirrhosis, a well-balanced, nutritious diet is one of the best ways to stay healthy. If you have fluid buildup, your doctor may tell you to cut back on salt.

Avoid alcohol and certain medications, supplements, and herbs. Ask your doctor what’s safe for you.

Read Also: How Is Hepatitis C Transferred From Person To Person

What Causes Hepatitis In General

  • Virus and other infections
  • Autoimmune response
  • Ischemia
  • Metabolic disorders
  • An acute illness caused by the hepatitis A virus .
  • Transmitted through food and water contaminated by feces of infected people.
  • An acute or chronic infection caused by the hepatitis B virus .
  • Transmitted through contact with infectious body fluids. It can be sexually transmitted or transmitted through infected needles.
  • An acute or chronic illness caused by the hepatitis C virus .
  • Transmitted through contact with infectious body fluids. It can be sexually transmitted or transmitted through infected needles.
  • Hepatitis D
  • Caused by the hepatitis D virus .
  • Transmitted through contact with infected blood.
  • It is rare, but very serious.
  • It only occurs in the presence of hepatitis B. HDV cannot multiply in the absence of HBV.
  • An acute disease caused by the hepatitis E virus .
  • Like HAV, it is transmitted through food and water contaminated by the feces of infected people.
  • Can Hepatitis C Worsen Existing Diabetes

    Hepatitis C: Causes and Treatment AMITA Health on Living Healthy Chicago Medical Minute

    Individuals with diabetes must maintain balanced insulin and blood sugar levels to manage the condition. This is known as maintaining glycemic control. Normally, people achieve glycemic control by carefully monitoring their insulin and blood sugar levels, and by receiving insulin injections.

    Research from 2017 states that a HCV infection can decrease glycemic control, which can worsen diabetes. However, the researchers found that people with both HCV and diabetes who received successful antiviral treatment improved significantly, and required less insulin as a result.

    90% of cases with few side effects. Most courses of treatment last from 812 weeks.

    Early testing and treatment for HCV is important, especially for those who either have, or are at risk for, diabetes. However, DAA treatment may cause changes in insulin or blood sugar levels as the virus clears, which could result in unexpected symptoms.

    For this reason, people with HCV and diabetes should carefully monitor their blood sugar levels during HCV treatment, and alert a doctor immediately if they experience the symptoms of high or low blood sugar levels. If DAA treatment improves their diabetes, they may need to adjust the amount of insulin they take.

    Whether a person is undergoing HCV treatment or not, managing diabetes can be more complicated if someone has the virus, due to its impact on the liver.

    Also Check: Is Hepatitis A Sexually Transmitted Disease

    How Is Hepatitis C Treated

    There are some very effective options for the treatment of hepatitis C infection. They are listed on the Medicare PBS , which makes them available at a much lower cost.

    Newer treatments differ from those available previously:

    • they cure more than 95% of people
    • their side effects are minimal
    • treatments last just 8 to 12 weeks
    • they involve just a few pills each day, with no injections required

    Curing hepatitis C means clearing the virus from the body. It helps reduce liver inflammation and can also help reverse scarring and cirrhosis. You can be re-treated if your treatment doesnt work the first time.

    You should check with your doctor before taking any other medication or supplements, and whether you need vaccinations against hepatitis A and hepatitis B. You should also avoid alcohol if you have hepatitis. If you have liver damage, you may also need to see a liver specialist

    For more information on how to get treatment, contact the National Hepatitis Info Line on 1800 437 222.

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