Monday, May 20, 2024

Is Hepatitis B Is Curable Or Not

How Is Hepatitis B Spread

Viral hepatitis (A, B, C, D, E) – causes, symptoms, diagnosis, treatment & pathology
  • Having unprotected sex.
  • Sharing or using dirty needles for drug use, tattoos or piercing.
  • Sharing everyday items that may contain body fluids, including razors, toothbrushes, jewelry for piercings and nail clippers.
  • Being treated medically by someone who does not use sterile instruments.
  • Being bitten by someone with the infection.
  • Being born to a pregnant woman with the infection.

Hepatitis B is not spread by:

  • Kissing on the cheek or lips.
  • Coughing or sneezing.
  • Hugging, shaking hands or holding hands.
  • Eating food that someone with the infection has prepared.

How Do I Get Hepatitis B Treatment

Usually for adults, hepatitis B goes away on its own and you wont need treatment. Your doctor might tell you to rest, eat well, and get plenty of fluids. You may also get medicines to help with any symptoms you might have but be sure to talk with your doctor or nurse before taking anything.

If you have chronic hepatitis, there are medicines you can take to treat it. Your doctor will tell you about your options and help you get whatever treatment you need.

How Do You Get Hepatitis C

Just like hepatitis B, you can get this type by sharing needles or having contact with infected blood. You can also catch it by having sex with somebody whos infected, but thats less common.

If you had a blood transfusion before new screening rules were put in place in 1992, you are at risk for hepatitis C. If not, the blood used in transfusions today is safe. It gets checked beforehand to make sure its free of the virus that causes hepatitis B and C.

Its rare, but if youre pregnant and have the disease, its possible to pass it to your newborn.

There are some myths out there about how you get hepatitis C, so lets set the record straight. Its not spread by food and water . And you canât spread it by doing any of these things:

See your doctor as soon as possible if you have any of these symptoms.

Sometimes, people have no symptoms. To be sure you have hepatitis, youâll need to get tested.

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Is There A Cure For Hepatitis B

The long and short answer is that there is not yet a cure for hepatitis B. Understanding why requires insight into the virus itself and the challenges cure researchers face.

Hepatitis B is an infectious disease caused by the hepatitis B virus . While most people exposed to hepatitis B will spontaneously clear the virus soon after infection, a proportion will go on to develop a chronic infection.

Of these, around one in four will develop severe liver complications, including cirrhosis and liver cancer, typically years after the initial infection.

Efforts to find a cure for hepatitis B have been underway since the virus was first identified by scientists at the National Institutes of Health in 1966. It soon became clear, however, that numerous hurdles would need to be overcome before an actual cure could be achieved. Chief among these are:

What Is Hepatitis B

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Hepatitis B is a liver infection caused by the hepatitis B virus that can affect people of all ages and is commonly found throughout the world.

Around the world, there are about 292 million infected people. The United States alone exceeds 2 million infections.

2 types of hepatitis B

  • Acute: An initial infection caused by the hepatitis B virus. Most people can recover from this acute infection.
  • Chronic: If the infection lasts for more than six months, it is termed chronic hepatitis B, which is the type that leads to severe liver inflammation, scarring, and liver cancer.
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    How Long Does It Last

    According to the World Health Organization , the complete vaccine series induces protective antibody levels in of the infants, children, and adolescents who receive it.

    Immune memory induced by the HBV vaccine can last for in healthy people. That said, studies into the duration of the protection that the vaccine offers are ongoing.

    Take Precautions To Avoid Hbv

    Other ways to reduce your risk of HBV include:

    • Know the HBV status of any sexual partner. Don’t engage in unprotected sex unless you’re absolutely certain your partner isn’t infected with HBV or any other sexually transmitted infection.
    • Use a new latex or polyurethane condom every time you have sex if you don’t know the health status of your partner. Remember that although condoms can reduce your risk of contracting HBV, they don’t eliminate the risk.
    • Don’t use illegal drugs. If you use illicit drugs, get help to stop. If you can’t stop, use a sterile needle each time you inject illicit drugs. Never share needles.
    • Be cautious about body piercing and tattooing. If you get a piercing or tattoo, look for a reputable shop. Ask about how the equipment is cleaned. Make sure the employees use sterile needles. If you can’t get answers, look for another shop.
    • Ask about the hepatitis B vaccine before you travel. If you’re traveling to a region where hepatitis B is common, ask your provider about the hepatitis B vaccine in advance. It’s usually given in a series of three injections over a six-month period.

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    What To Expect From Your Doctor

    Your health care provider is likely to ask you a number of questions, including:

    • When did your symptoms begin?
    • Have you ever developed jaundice symptoms, including yellowing of the eyes or clay-colored stool?
    • Were you previously vaccinated for hepatitis B?
    • Have your symptoms been continuous or occasional?
    • How severe are your symptoms?
    • What, if anything, seems to improve your symptoms?
    • What, if anything, appears to worsen your symptoms?
    • Have you ever had a blood transfusion?
    • Do you inject drugs?

    Hepatitis B And Pregnancy

    Hepatitis A and B

    If youâre pregnant, you might pass the virus to your baby at birth. Itâs less likely to happen during your pregnancy.

    If your baby gets the virus and isnât treated, they could have long-term liver problems. All newborns with infected mothers should get hepatitis B immune globulin and the vaccine for hepatitis at birth and during their first year of life.

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    Check If You Have Hepatitis B

    Symptoms of hepatitis B infection include:

    • a high temperature
    • pain in your upper tummy
    • feeling sick or being sick
    • patches of raised skin that may be itchy
    • yellowing of the skin and whites of the eyes

    The infection usually lasts for 1 to 3 months and most people either have no symptoms or mild symptoms. If the infection lasts longer than 6 months it is called chronic hepatitis B.

    How You Can Get Hepatitis B

    You can get hepatitis B from:

    • injecting drugs using shared needles
    • being injured by a used needle
    • having a tattoo or piercing with unsterilised equipment
    • having a blood transfusion in a country that does not check blood for hepatitis B. Blood transfusions in the UK are checked for hepatitis B.

    If you’re pregnant and have hepatitis B, you can also pass it onto your baby during pregnancy or birth.

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    Hbsag Clearance After Na Treatment

    There are few large or conclusive studies on the clearance of HBsAg after NA treatment, and some of these studies are single-centre retrospective studies. Kim et al. reported a clearance rate of 1% or less in 110 CHB patients who were treated with ETV/LAM for approximately 1 year. A retrospective study by Yip et al. reported an HBsAg clearance rate of 2.1% after an average follow-up of 4.8 years in 20,263 CHB patients treated with ETV/TDF for longer than 6 months. Wong et al. retrospectively evaluated 1072 CHB patients on antiviral therapy for approximately 6 years and found an HBsAg clearance rate of 4.58%. This study found no significant difference in the clearance rate between HBeAg-positive and HBeAg-negative patients, but the rate in patients with cirrhosis was significantly lower than patients without cirrhosis . These results suggested that the clearance rate of non-cirrhosis patients was higher after NA treatment, which is not consistent with the results of patients who experienced spontaneous clearance. Compared to patients with normal baseline ALT, patients with higher ALT levels had significantly higher rates of achieving HBsAg clearance. In general, the clearance rate may increase with the extension of treatment in CHB patients, but the overall rate with currently available NA treatment is low. The HBsAg clearance rates were 1.45.1% after an average follow-up of 27 years after NA treatment .

    European Commission And Thervacb Join Forces

    Pin on Hepatitis A, B, C

    The role of viral hepatitis as a public health threat has long been underestimated. Only very recently, the United Nations in their 2030 Agenda for Sustainable Development called for international action to combat viral hepatitis and reduce the disease burden. The major killer is the hepatitis B virus causing liver cirrhosis and liver cancer. Worldwide 880,000 humans die each year from the consequences of an HBV infection.

    A prophylactic vaccine is available to prevent HBV infection, but more than 3% of the worlds population are chronically infected and do not profit from that vaccine anymore. For those suffering from chronic hepatitis B, until today no curative treatment option exists.

    The European Commission therefore selected the project TherVacB led by Helmholtz Zentrum München for a five-year funding within the Horizon 2020 program. A consortium of leading virologists, immunologists and physicians specialized in treating viral hepatitis, will use a newly designed therapeutic vaccine, TherVacB, as an immunotherapy to cure HBV. TherVacB will be evaluated in a three-year clinical trial starting in 2022 conducted in Europe and in Africa. Integration of a partner site in Tanzania shall help building local capacities for diagnosing and treating hepatitis B and support an important goal of the consortium to raise awareness for hepatitis B.

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    Treatment For Suspected Exposure

    Anyone who has had potential exposure to HBV can undergo a postexposure prophylaxis protocol.

    This consists of HBV vaccination and hepatitis B immunoglobin . Healthcare workers give the prophylaxis after the exposure and before an acute infection develops.

    This protocol will not cure an infection that has already developed. However, it decreases the rate of acute infection.

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    Is Hepatitis B Curable Or Not

    The most common way this gets transmitted is through an infected pregnant woman to their baby during childbirth. This is due to the exchange of blood that occurs between mother and baby. Some of the other common ways it gets transmitted include:

  • Unsterile medical / dental equipment
  • Unprotected sex
  • Unsterile needles
  • Sharing personal items with other individuals such as razors, body jewelry, tooth brushes, nail clippers, etc.
  • Hepatitis B is also referred to as silent epidemic. This is because it does not show any symptoms among individuals newly or chronically infected. They can unintentionally spread the virus to others. These individuals can continue to spread hepatitis B silently.

    Symptoms or no symptoms, people with hepatitis B can transfer the illness to other individuals and their liver is still being silently damaged. The stage can turn into serious liver ailment such as liver cancer or cirrhosis.

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    How Long Can You Live If You Have Hepatitis B

    Although those with chronic hepatitis B infection live with an increased risk of developing liver disease later in life, many should expect to live long and healthy lives. Someone with chronic hepatitis B should be seen by a liver specialist every six months, or more often as needed.

    How do you get rid of hepatitis B virus naturally?

    Of all the natural remedies used for hep B, milk thistle is the most popular, and the most tested. This herb is a common ingredient in supplement blends that promote liver health. Milk thistle is a plant from the aster family.

    How long does it take to treat hepatitis B?

    Duration of treatment is at least 1 year with lamivudine and adefovir longer duration of treatment is needed in most patients, but the optimal duration of treatment and the criteria for stopping treatment have not been established.

    How Far Have We Got

    Vacunación contra la hepatitis B en las primeras 24 horas de vida

    Some exciting research is underway around the world, including the recent identification of the cell receptor which allows the virus to infect the body. This has enabled studies of the complete virus replication cycle including the viral reservoir that is untouched by current therapies.

    New approaches to a possible cure include mechanisms to block the virus entry into the cell and to stop the virus from making the proteins it needs to replicate and infect new cells.

    Studies are also underway to enhance patients immune responses so their own natural defences can control or even eliminate the virus. This is similar to immunotherapies already being used to treat some cancers.

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    Its likely a hepatitis B cure will require a dual-pronged approach, directly targeting the virus while also enhancing the immune response in people who are infected.

    The goal is to reduce the amount of virus in the body and restore the persons immune responses. This is called a functional cure and is similar to what happens when a person naturally gets rid of the virus. It would also mean they didnt need to take drugs any more.

    Some of these approaches are now in early stage human clinical trials. More than 30 drugs have been developed and are being tested in people with chronic hepatitis B. However, much more work needs to be done to achieve a cure.

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    How Is Hepatitis B Treated

    Your healthcare provider will treat you based on what type of hepatitis B you have, acute or chronic.

    Acute hepatitis B infections

    If you develop an acute form of the condition, you probably wont need medical treatment. Instead, your doctor will likely suggest that you get plenty of rest, drink lots of fluids and maintain a healthy diet to support your body as it fights off the infection.

    Chronic hepatitis B infections

    If you have chronic hepatitis B, you might be a candidate for drug therapy. Usually, drug therapy is used only if you have active liver disease. There are seven drugs that are approved by the U.S. Food and Drug Administration to treat hepatitis B. Two are injectable forms of interferon, while the five other antivirals are tablets.

    You will need to take these medications every day. They help by slowing the viruss ability to multiply in your system. This helps reduce swelling and liver damage. Youll need to be regularly monitored for early signs of liver damage and liver cancer. Your healthcare provider will want to see you once or twice a year.

    The Hepatitis B Vaccine

    Getting the hepatitis B vaccine is one of the most effective ways to prevent hepatitis B. Its usually administered in two, three, or four doses. In many countries, infants receive their first dose of the vaccine at birth.

    The Centers for Disease Control and Prevention recommends that infants receive their first dose of the vaccine at birth and finish all doses at 6 to 18 months old.

    The CDC also recommends all children under the age of 19 years old be vaccinated if they havent already received the vaccination.

    Adults can also get the hepatitis B vaccine. The vaccine is generally recommended if you have an increased risk of contracting the virus. Some of these risk factors include:

    • traveling to or living in a region where hepatitis B is common
    • being sexually active with more than one partner or with a partner who has hepatitis B
    • working in a medical setting or other workplaces where youre exposed to bodily fluids
    • using intravenous drugs and sharing drug equipment
    • having chronic liver disease, a human immunodeficiency virus infection, a hepatitis C infection, diabetes, or kidney disease on dialysis

    If youve been exposed to the hepatitis B virus and havent been vaccinated, try to see a doctor right away. They can administer the first dose of the vaccine, though youll need to follow up to receive the remaining doses over the next few months.

    They may also prescribe a medication called

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    What Is Viral Hepatitis

    Hepatitis means inflammation of the liver. The liver is an organ in the right upper quadrant of the abdomen that processes nutrients, filters the blood and fights infections. When the liver is inflamed or damaged, its function can be adversely affected. The most frequent cause of hepatitis is a virus. The most common types of viral hepatitis are hepatitis B virus and hepatitis C virus . It is estimated that in the United States as of 2019, 2.2 million to 4.7 million persons are infected with HCV and 850,000 to 2.2 million are chronically infected with HBV.

    CDC Definition: Hepatitis is a vaccine-preventable, communicable disease of the liver caused by the hepatitis A virus . It is usually transmitted person-to-person through the fecal-oral route or consumption of contaminated food or water. Hepatitis A is a self-limited disease that does not result in chronic infection. Most adults with hepatitis A have symptoms, including fatigue, low appetite, stomach pain, nausea, and jaundice, that usually resolve within 2 months of infection most children less than 6 years of age do not have symptoms or have an unrecognized infection. Antibodies produced in response to hepatitis A infection last for life and protect against reinfection. The best way to prevent hepatitis A infection is to get vaccinated.

    Who Are Hepatitis B Carriers

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    Hepatitis B carriers are people who have the hepatitis B virus in their blood, even though they dont feel sick. Between 6% and 10% of those people whove been infected with the virus will become carriers and can infect others without knowing it. There are over 250 million people in the world who are carriers of HBV, with about 10% to 15% of the total located in India. Children are at the highest risk of becoming carriers. About 9 in 10 babies infected at birth become HBV carriers, and about half of children who are infected between birth and age 5 carry the virus. A blood test can tell you if you are a hepatitis B carrier.

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