What Is Hepatitis Panel Acute With Reflex
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Hepatitis Panel, Acute with Reflex to HBsAg Confirmation. Order to evaluate viral etiology in patients with acute hepatitis. Not recommended for screening asymptomatic patients. Panel includes HAV IgM, HBV core antibody IgM, HBV surface antigen, HCV antibody.
Also Know, how long does a hepatitis panel take to get results? Normal results are negative, meaning you don’t have the IgM antibody in your blood. The antibody shows up 3 to 4 weeks after you are exposed to the virus. The antibody peaks about a month after symptoms appear, and typically can’t be detected 3 to 4 months after symptoms begin.
Correspondingly, what does a hepatitis panel test for?
A hepatitis panel is a blood test used to find markers of hepatitis infection. Hepatitis causes inflammation of the liver. There are different hepatitis panels. Some tests look for proteins that the body makes to fight the infection.
What is hepatitis B panel?
The Hepatitis B Panel of Blood TestsHBsAg – A “positive” or “reactive” HBsAg test result means that the person is infected with hepatitis B. This test can detect the actual presence of the hepatitis B virus in your blood.
What Does The Test Measure
An acute viral hepatitis panel includes several tests that measure antigens and antibodies. Antigens are foreign substances such as proteins of the virus itself, while antibodies are substances produced by the immune system in response to the viral infection.
An acute viral hepatitis panel tests for antigens and/or antibodies of hepatitis A, B, and C:
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Hepatitis Panel Acute With Reflex To Confirmation
CPT Code: 80074
Hepatitis B Surface Antigen with Reflex to Confirmation
Hepatitis B Core Antibody
Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR
Hepatitis B Surface Antigen: Positive samples will be confirmed based on the manufacturers FDA approved recommendations at an additional charge : 87341).
If Hepatitis C Antibody is reactive, then Hepatitis C Viral RNA, Quantitative, Real-Time PCR will be performed at an additional charge : 87522).
Alternative Name: Acute Hepatitis Panel with ReflexABN Requirement: No
Collection Instructions: Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.
Stability:
Ambient : 72 hoursRefrigerated : 14 daysFrozen : 21 days
Methodology: Immunoassay
Turn Around Time: 1 to 3 days
Reference Range: See individual tests
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What Happens During A Hepatitis Panel
A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
At-home testing kits are available for hepatitis B and C. Usually the test kit will include a sharp device, to prick your finger so you can collect a drop of blood to send to a lab for testing. For more information on at-home testing for hepatitis, talk to your provider.
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Discussing Screening Results With Clients
The medical personnel who ordered or arranged the screening test, not counselors, usually explain the results. Hepatitis screening should be part of the intake physical examination in an opioid treatment program, and medical personnel may report the results. However, the client may want to discuss the results with the counselor or ask the counselor questions.
Anxiety might interfere with some clients ability to comprehend or retain information, which might need to be repeated.
Suggestions for conversations with clients when the test results are negative include the following:
- Explain results clearly and simply: So the HCV screening result was negative? This means that, as of 6 months ago, you did not have .
- Emphasize that a negative result to an HCV test does not indicate to and that the client should take precautions to avoid . If a relapse to drug use occurs, advise clients to avoid sharing any drug paraphernalia or equipment. Specify that this includes cookers, cotton, water, needles, syringes, pipes, and straws.
- Emphasize the importance of getting HAV and HBV vaccinations. Provide information about the availability of low- or no-cost vaccinations.
Clients whose screening test results are positive for will need additional tests and examinationsusually with doctors who specialize in diseases of the liver to get accurate diagnoses and to determine their health status and the extent of liver damage. These tests are described in .
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The Treatment Programs Role In The Screening Process
Medical staff members at substance abuse treatment programs might assume the primary role for screening individuals for and explaining the screening process and test results. Opioid treatment programs with medical staff members should screen for and C at intake and periodically as indicated. In programs without onsite medical staff, clients may be referred elsewhere for screening with minimal involvement of the substance abuse treatment program.
Regardless of the type of program, counselors should have a basic understanding of the importance of screening, the screening process, and the meaning of the results. Counselors can encourage clients referred for screening to follow through and complete the screening and evaluation process . Clients might feel anxious about being diagnosed with hepatitis, and they might delay or avoid getting screened.
Counseling Practices That Educate Support And Motivate Clients Undergoing Screening
Clients might need help deciding whether to get screened, understanding the test results, and determining their next steps. Even when services offered through the substance abuse treatment program are limited, discussing testing with clients presents an opportunity for counselors to motivate clients for change by confronting substance use and by making choices that improve their overall health. However, this may also be true when services are offered on-site through substance abuse treatment programs. A study at one methadone clinic that offered hepatitis screening and vaccination revealed that although the majority of clients completed screening , only 54.7 percent of clients who lacked for hepatitis A received vaccinations and only 2.9 percent of clients who lacked immunity for received vaccinations .
The Consensus Panel makes the following general recommendations while recognizing that, in some programs, the counselors role may be limited:
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For Hepatitis C Testing
As a part of the hepatitis panel test, the Hepatitis C analysis looks for the presence of antibodies in response to the Hepatitis C virus in the bloodstream. These antibodies are detectable 4-10 weeks after infection, where the positive result tests are followed by other tests measuring the amount of genetic material of the Hepatitis C virus.
For Hepatitis B Testing
While testing for Hepatitis B, the hepatitis panel test includes a series of tests detecting hepatitis B surface antigen and IgM hepatitis B core antibodies. The hepatitis B surface antigens are discernable from 1-10 weeks after exposure before the appearance of the symptoms. They remain detectable for up to 6 months in people already recovered from acute infection. The IGM hepatitis B core antibodies are noticeable for up to 2 years after an acute infection, enduring flare-ups as well. If your doctor suspects chronic Hepatitis B, he may ask for follow-up testing to prepare a treatment plan.
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When Should I Get An Acute Viral Hepatitis Panel
An acute viral hepatitis panel may be recommended when a patient has symptoms of hepatitis, or if a person has a suspected or known exposure to a hepatitis virus. Although some patients with hepatitis have no symptoms, when present symptoms may include:
- Clay-colored bowel movements
Patients that have an acute hepatitis infection may begin to experience symptoms between 2 weeks and 6 months after becoming infected. Patients with a chronic hepatitis infection may not experience symptoms until many years after infection.
Doctors may also recommend an acute viral hepatitis panel in patients with abnormal results on tests that evaluate liver function, such as a liver panel.
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Acute Viral Hepatitis Panel
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Can I Take The Test At Home
Although an acute viral hepatitis panel cannot be conducted at home, at-home test kits are available for some tests within this panel. These kits involve obtaining a blood sample by pricking a finger with a sharp object, called a lancet, and then sending it to a laboratory for testing.
At-home test options include:
- At-home hepatitis B testing: At-home hepatitis B testing looks for hepatitis B surface antigen.
- At-home hepatitis C testing: At-home hepatitis C testing detects hepatitis C antibodies and does not include hepatitis C RNA testing.
Several at-home hepatitis testing companies sell test panels that detect both hepatitis B and C. There is no at-home test available for hepatitis A. Testing for hepatitis A requires blood to be drawn by a health care professional.
Because hepatitis testing can involve many tests, testing for hepatitis at-home is not a substitute for care provided by a health care professional. Results of at-home tests may need to be confirmed through laboratory-based testing.
What Does A Hepatitis Panel Involve
Hepatitis panels are simple blood tests. They do not involve any preparation and have a very low risk of side effects.
To perform the test, a healthcare professional will insert a needle into a vein in the arm. They will collect a small blood sample in a test tube and seal it. The needle may sting a little, but the process takes only a few minutes. A person may feel a small amount of pain or bruising around the vein, but this should subside quickly.
People can also get at-home testing kits for hepatitis. These come with a sterile lancet that a person uses to prick their finger to collect the blood sample.
When using at-home kits, be sure to take safety precautions to prevent others from coming into contact with blood. Even dry blood or tiny amounts of blood can potentially transmit HBV or HCV to others.
Dispose of items that come into contact with blood in a sealed bag and wash the blood from the skin using soap. Completely cover the finger prick wound with a sterile dressing until it heals.
- of the population have hepatitis B and have not had a vaccination
- spent time in a facility that had a hepatitis outbreak, such as a hospital or prison
- received a blood transfusion that did not undergo hepatitis screening
In the United States, screening eliminated HCV from donated blood in 1992. People who received blood transfusions before 1992 should ask their doctor for a hepatitis C test.
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Where Can I Find An Acute Hepatitis Panel Test Near Me
Check our lab finder to locate a collection site in your area.
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
Detection Period:
- Dark-colored urine or pale stool
- Itching and skin irritation
Hepatitis testing can also be done when someone is concerned they have recently had an exposure even if they are not currently experiencing symptoms. Hepatitis A is typically spread through exposure to fecal matter or contaminated water or food. Hepatitis B is spread through infected blood or bodily fluids, usually through sexual contact. Hepatitis C is typically spread through contaminated blood by sharing needles for intravenous drug use, using improperly sterilized tattoo or piercing equipment, and sexual contact.
Turnaround time for the Acute Hepatitis Panel is typically 1 business day.
Hepatitis C Reflex Testing
To ensure complete and timely diagnosis of HCV, HCV reflex testing is recommended following a reactive hepatitis C antibody screening test. Reflex testing means the laboratory will perform the hepatitis C antibody test, and if the result is positive, the laboratory will immediately perform an HCV RNA test on the same specimen. If the subsequent HCV RNA test is negative, HCV infection is effectively ruled out for most patients. If the reflex HCV RNA test is positive, a diagnosis of active HCV infection has been confirmed, and the individual should be referred directly for HCV care and treatment.
Reflex testing obviates the need for the patient to return for follow-up testing should the initially HCV antibody test be reactive. If the RNA test is negative, the work-up is done, and the patient may be reassured.
- Rationale for reflex testing:
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Hepatitis Panel/acute Hepatitis Panel
Please Note: This may not be an exhaustive list of all applicable Medicare benefit categories for this item or service.
This panel consists of the following tests:
- Hepatitis A antibody , IgM Antibody
- Hepatitis B core antibody , IgM Antibody
- Hepatitis B surface antigen and
- Hepatitis C antibody.
Hepatitis is an inflammation of the liver resulting from viruses, drugs, toxins, and other etiologies. Viral hepatitis can be due to one of at least five different viruses, designated Hepatitis A, B, C, D, and E. Most cases are caused by Hepatitis A virus , Hepatitis B virus , or Hepatitis C virus .
HAV is the most common cause of hepatitis in children and adolescents in the United States. Prior exposure is indicated by a positive IgG anti-HAV. Acute HAV is diagnosed by IgM anti-HAV, which typically appears within four weeks of exposure, and which disappears within three months of its appearance. IgG anti-HAV is similar in the timing of its appearance, but it persists indefinitely. Its detection indicates prior effective immunization or recovery from infection. Although HAV is spread most commonly by fecal-oral exposure, parenteral infection is possible during the acute viremia stage of the disease. After exposure, standard immune globulin may be effective as a prophylaxis.
Indications
Limitations
Is There Anything Else I Should Know
The tests that are typically included in an acute viral hepatitis panel may not always be able to tell whether someone has had a previous hepatitis infection or has developed antibodies in response to a vaccine. Usually other types of tests are performed to provide this type of information. See the individual articles on Hepatitis A Testing, Hepatitis B Testing or Hepatitis C Testing for more on this.
The presence of hepatitis A IgM antibodies in the blood are considered diagnostic for acute infection with hepatitis A when the test information is combined with a persons signs and symptoms. When the hepatitis screening test is performed for people who do not have symptoms of acute hepatitis, the presence of hepatitis A IgM antibodies may represent a false-positive result. Therefore, the Centers for Disease Control and Prevention has recommended against using the test for screening in people without acute hepatitis symptoms to decrease the possibility of false-positive results.
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What Do The Results Mean
Labs report hepatitis panel results in different ways:
- A negative or normal result means you probably dont have a hepatitis infection.
- A positive or abnormal result may mean you have a hepatitis infection now or had an infection in the past.
For hepatitis A and B, your test results will say whether you have a current or past infection, or if you have immunity because you had a vaccination.
If your test shows that you have signs of hepatitis C, you will need another test to find out if you are infected now, or if you had an infection in the past. There is no vaccination for hepatitis C.
You may need more tests to confirm a diagnosis and to see how hepatitis has affected your liver. If you have questions about your results, talk with your provider.
Expertise In Infectious Diseases
The history of bioMérieux is directly linked to the fight against infectious diseases, which has been our priority for over 50 years. Our research teams constantly focus on pushing back the frontiers of disease detection by dedicating the majority of their activities to the prevention and diagnosis of infection risk.
bioMérieux provides tests for the early detection of numerous diseases, including HIV/AIDS, hepatitis, tuberculosis, respiratory infections, CNS infections, sepsis, C. Difficile
Hepatitis E Virus is the most common cause of acute viral hepatitis worldwide, with 20 million infections and 3.3 million acute cases every year. Hepatitis E is a food- and water-borne infection. The risk is higher in developing countries with unsafe water and poor sanitation, but you can catch it anywhere. In Europe, the number of reported cases has increased 10-fold over the last decade.
In its fulminant form, Hepatitis E can be fatal in pregnant women, infants or patients with pre-existing liver disease. It is therefore important to think E for all patients with clinical signs and symptoms of Hepatitis. Our new VIDAS® Anti-HEV IgM and Anti-HEV IgG assays allow you to perform in-house testing for better patient management.
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