Thursday, October 6, 2022

Causes And Symptoms Of Hepatitis

How Hepatitis A Is Spread

Hepatitis, Causes, Signs and Symptoms, Diagnosis and Treatment.

Hepatitis A is most commonly spread when someone eats food or drinks water that contains the hepatitis A virus. This is more likely when travelling outside Canada in areas of the world where hepatitis A is more common. Contaminated sources may include:

  • ice
  • raw or frozen fruits and vegetables

Hepatitis A can also spread:

  • from person to person through:
  • sexual contact with an infected person
  • contact with the feces of an infected person
  • blood transfusions or sharing needles for drug use
  • changing diapers or cleaning up stool from an infected person

Even if you do not have symptoms, you can still infect others. Infected infants and children are more likely to be without symptoms than infected adults.

You can spread the virus starting 2 weeks before you show any symptoms. You can continue to infect others until about a week after you get jaundice .

What Should You Know About Hepatitis B Before You Travel

Hepatitis B is quite common in China and other Asian countries, where as many as 1 in 12 people have the virus, though many dont know it. Before traveling to those places, you should make sure youve been vaccinated against the virus.

In addition to getting the vaccine, you can take these additional precautions to reduce your risk of contracting the virus:

  • Refrain from taking illegal drugs.
  • Always use latex or polyurethane condoms during sex.
  • Make sure new, sterile needles are used during all piercings, tattoos and acupuncture sessions.
  • Avoid direct contact with blood and bodily fluids.
  • Know the HBV status of all your sexual partners.
  • Ask your doctor about possible vaccination before you travel to a place where hepatitis B is common.

A note from Cleveland Clinic

Hepatitis B is a liver disease that can cause serious damage to your health. One reason that is dangerous is that it can easily go undetected for years while damaging your liver. Talk with your healthcare provider about being tested for hepatitis B if you have any reason to believe that you were not vaccinated or if you have engaged in risky behavior. If you do test positive, follow the directions from your healthcare provider so that you can live a longer, healthier and happier life.

Last reviewed by a Cleveland Clinic medical professional on 07/09/2020.

References

Who Is At Risk For Hepatitis A

Travelers to countries with high infection rates and the inhabitants of those countries are at higher risk for developing hepatitis A. The Centers for Disease Control issues travel advisories that identify the countries with outbreaks or endemic hepatitis A. Eating raw or uncooked foods increases the risk for hepatitis A.

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Symptoms Of Acute Viral Hepatitis

Acute viral hepatitis can cause anything from a minor flu-like illness to fatal liver failure Liver Failure Liver failure is severe deterioration in liver function. Liver failure is caused by a disorder or substance that damages the liver. Most people have jaundice , feel tired… read more . Sometimes there are no symptoms. The severity of symptoms and speed of recovery vary considerably, depending on the particular virus and on the person’s response to the infection. Hepatitis A and C often cause very mild symptoms or none at all and may be unnoticed. Hepatitis B and E are more likely to produce severe symptoms. Infection with both hepatitis B and D may make the symptoms of hepatitis B even more severe.

Symptoms of acute viral hepatitis usually begin suddenly. They include

  • A poor appetite

People with acute viral hepatitis usually recover in 4 to 8 weeks, even without treatment. However, some people infected with hepatitis B or C develop chronic infections.

Willowbrook State School Experiments

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A New York University researcher named Saul Krugman continued this research into the 1950s and 1960s, most infamously with his experiments on mentally disabled children at the Willowbrook State School in New York, a crowded urban facility where hepatitis infections were highly endemic to the student body. Krugman injected students with gamma globulin, a type of antibody. After observing the temporary protection against infection this antibody provided, he then tried injected live hepatitis virus into students. Krugman also controversially took feces from infected students, blended it into milkshakes, and fed it to newly admitted children.

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Treatment Of Acute Viral Hepatitis

  • Supportive care

For most people with acute viral hepatitis, special treatment is not necessary. However, people with severe acute hepatitis may require hospitalization so that symptoms can be treated. If doctors suspect that fulminant hepatitis is developing, the person is hospitalized so that mental status can be monitored, liver tests can be done, and doctors can determine whether liver transplantation is needed.

After the first several days, appetite usually returns and people do not need to stay in bed. Severe restrictions of diet or activity are unnecessary, and vitamin supplements are not required. Most people can safely return to work after the jaundice clears, even if their liver test results are not quite normal.

People with hepatitis should not drink alcohol until they have fully recovered.

The infected liver may not process drugs normally. So a doctor may need to stop a drug or reduce the dosage of a drug that could accumulate to harmful levels in the body . Thus, people with hepatitis should tell their doctor all the drugs they are taking , so that the dosage of the drug can be adjusted if necessary.

If itching occurs, cholestyramine, taken by mouth, is often effective.

Hepatitis B And Pregnancy

If youâre pregnant, you might pass the virus to your baby at birth. Itâs less likely to happen during your pregnancy.

If your baby gets the virus and isnât treated, they could have long-term liver problems. All newborns with infected mothers should get hepatitis B immune globulin and the vaccine for hepatitis at birth and during their first year of life.

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How Is Hepatitis B Diagnosed

There are three main ways to diagnose HBV infection. They include:

  • Blood tests: Tests of the blood serum shows how your bodys immune system is responding to the virus. A blood test can also tell you if you are immune to HBV.
  • Abdominal ultrasound: An ultrasound uses sound waves to show the size and shape of your liver and how well the blood flows through it.
  • Liver biopsy: A small sample of your liver tissue is removed though a tiny incision and sent to a lab for analysis.

The blood test that is used to diagnose hepatitis B is not a test that you get routinely during a medical visit. Often, people whove become infected first learn they have hepatitis B when they go to donate blood. Blood donations are routinely scanned for the infection.

The virus can be detected within 30 to 60 days of infection. About 70% of adults with hepatitis B develop symptoms, which tend to appear an average of 90 days after initial exposure to the virus.

What Happens With Hepatitis A

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Viral diseases generally are contagious. Hepatitis A is highly contagious. It usually is spread from person to person via a fecal-oral route, meaning via fecal contamination of food. It usually is a mild hepatitis, and many people do not know they are infected. The virus is eliminated by the body rapidly, and it does not cause long-term damage. Good hand washing hygiene helps prevent hepatitis A.

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What Is Hepatitis E

Hepatitis E, also called enteric hepatitis , is similar to hepatitis A, and more prevalent in Asia and Africa. It is also transmitted through the fecal-oral route. It is generally not fatal, though it is more serious in women during pregnancy and can cause fetal complications. Most patients with hepatitis E recover completely.

What Are The Common Types Of Viral Hepatitis

Although the most common types of viral hepatitis are HAV, HBV, and HCV, some clinicians had previously considered the acute and chronic phases of hepatic infections as “types” of viral hepatitis. HAV was considered to be acute viral hepatitis because the HAV infections seldom caused permanent liver damage that led to hepatic failure. HBV and HCV produced chronic viral hepatitis. However, these terms are outdated and not currently used as frequently because all of the viruses that cause hepatitis may have acute phase symptoms . Prevention techniques and vaccinations have markedly reduced the current incidence of common viral hepatitis infections however, there remains a population of about 1 to 2 million people in the U.S. with chronic HBV, and about 3.5 million with chronic HCV according to the CDC. Statistics are incomplete for determining how many new infections occur each year the CDC documented infections but then goes on to estimate the actual numbers by further estimating the number of unreported infections .

Hepatitis A

Hepatitis B

Hepatitis C

Types D, E, and G Hepatitis

Individuals who already have chronic HBV infection can acquire HDV infection at the same time as they acquire the HBV infection, or at a later time. Those with chronic hepatitis due to HBV and HDV develop cirrhosis rapidly. Moreover, the combination of HDV and HBV virus infection is very difficult to treat.

  • HIV patients
  • People with hemophilia who receive blood clotting factors

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When To See A Healthcare Provider

If you develop any of the symptoms of chronic hepatitis, liver damage, or liver cancer, see your healthcare provider. It takes only a blood test to detect the presence of a hepatitis virus in your body .

A blood test also can determine which hepatitis virus you’re infected with, which will determine what your treatment should be .

How Does Hepatitis B Spread

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Persons infected with hepatitis B can pass the virus to others through blood or body fluids. In the U.S., the most common way of becoming infected is through unprotected sex, although sharing an infected person’s needles to inject illicit drugs also is quite common. Less common ways are by contaminated razors or toothbrushes. As previously mentioned, hepatitis B is passed from infected mother to infant in over 90% of cases.

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What Is Involved In A Liver Transplant

A liver transplant is considered necessary when the liver is damaged and cannot function or in some cases of liver cancer. Your liver is very important. It is responsible for many functions related to making sure that your body stays healthy and is able to digest foods.

You may be eligible for a transplant if you have chronic hepatitis B infection or some of the diseases that may result from it, including liver cancer and cirrhosis. You will have to complete testing and be evaluated before being approved for a transplant. It is likely that you will be placed on a waiting list while an appropriate organ is found.

Donated livers come from two types of donors: living and deceased. Because the liver can regenerate, it is possible to use part of a liver for transplant. The remaining sections in both the donor and the receiver will grow into livers of adequate size.

People who get liver transplants must take anti-rejection drugs for the rest of their lives. These drugs make you more susceptible to infection. However, liver transplants have become more successful over time and continue to improve.

Symptoms Of An Acute Infection

Few people show symptoms during acute infection . These symptoms can include: fatigue tenderness or an aching feeling on the right side of the abdomen decreased appetite perhaps with weight loss flu-like symptoms nausea tendency to bruise or bleed easily jaundice rash dark-coloured urine and light or clay-coloured stools. These symptoms often go away after a short time.

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What Causes Autoimmune Hepatitis

Experts arent sure what causes autoimmune hepatitis. Studies suggest that certain genes make some people more likely to develop autoimmune diseases. In people with these genes, factors in the environment may trigger an autoimmune reaction that causes their immune system to attack the liver.

Researchers are still studying the environmental triggers that play a role in autoimmune hepatitis. These triggers may include certain viruses and medicines.

Some medicines can cause liver injury that resembles autoimmune hepatitis. In most cases, the liver injury goes away when the medicine is stopped. The most common medicines that cause liver injury that resembles autoimmune hepatitis are minocyclinean antibiotic used to treat acneand nitrofurantoinan antibiotic used to treat urinary tract infections. Telling your doctor the names of all the medicines you take, even over-the-counter medicines or herbal or botanical products, is important.

Molecular Sieves And Desiccants

Hepatitis A – Simple explained. Hepatitis A causes, symptoms, treatment, prognosis, transmission

Apart from distillation, ethanol may be dried by addition of a , such as , , or . The desiccants can be dried and reused. can be used to selectively absorb the water from the 95.6% ethanol solution. Molecular sieves of pore-size 3 , a type of , effectively sequester water molecules while excluding ethanol molecules. Heating the wet sieves drives out the water, allowing regeneration of their dessicant capability.

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How Does Hepatitis C Spread

Hepatitis C is transmitted primarily by infected blood, for example by sharing needles when injecting illicit drugs. The virus is spread much less commonly with tattoos or body piercing with a contaminated needle. Mothers pass the virus to their infants at birth, and the infant becomes chronically infected. The risk of spreading hepatitis C with unprotected sex is small, but having multiple sex partners, HIV, or rough sex increases the risk.

How Do Doctors Diagnose Hepatitis

Doctors mainly use blood tests and a physical exam to diagnose hepatitis. This includes your personal and family medical history. The most telltale sign of hepatitis is jaundicea yellow cast to the skin and whites of the eyes. This is due to increased levels of bilirubin, a yellow substance, in your blood and tissues. Jaundice is the most visible clue to liver inflammation, along with and pale stool.

A diagnosis of hepatitis may be delayed because the many other possible symptomssuch as abdominal pain, , nausea, and loss of appetiteare shared with many other, less serious conditions and may be ignored.

If your doctor suspects you have hepatitis, he or she will order these blood tests:

  • Complete blood count to evaluate your blood health
  • Liver function tests to evaluate markers of liver inflammation and damage, including liver enzymes, total protein, and bilirubin
  • Virology tests to diagnose the specific type of viral hepatitis

Other tests your doctor may order include:

  • Autoimmune antibody panel to help diagnose autoimmune hepatitis
  • Genetic analysis for genetic and inherited conditions that can lead to hepatitis, such as Wilsons disease and
  • Toxicology tests, including ethanol and drug testing

Diagnostic procedures for chronic hepatitis may include a liver to determine the severity of inflammation and scarring .

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What Is Hepatitis C

Hepatitis C is a viral infection that causes liver inflammation and damage. Inflammation is swelling that occurs when tissues of the body become injured or infected. Inflammation can damage organs.

Viruses invade normal cells in your body. Many viruses cause infections that can be spread from person to person. The hepatitis C virus spreads through contact with an infected persons blood.

Hepatitis C can cause an acute or chronic infection.

Although no vaccine for hepatitis C is available, you can take steps to protect yourself from hepatitis C. If you have hepatitis C, talk with your doctor about treatment. Medicines can cure most cases of hepatitis C.

Here Are Some Of The Specific Ways The Hepatitis A Virus Can Spread:

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# Eating food handled by someone with the virus who doesnt thoroughly wash his or her hands

# Eating food prepared by someone with the hepatitis A virus

# Eating sewage-contaminated raw shellfish

# Coming in contact with hepatitis A-infected fecal matter

Risk factors of Hepatitis A?

Youre at increased risk of hepatitis A if you:

# Travel or work in areas of the world where hepatitis A is common

# Are HIV positive

# Attend child care or work in a child care center

# Have any type of sexual contact with someone who has hepatitis A

# Are experiencing homelessness

# Have a clotting-factor disorder, such as hemophilia

# Use any type of illegal drugs

# Live with another person who has hepatitis A

# Work with primates

Also at higher risk are:

# Men who have sex with men

# Kids in child care and their teachers

Diagnosis of Hepatitis A?

Your doctor will first ask about your symptoms and check for high levels of liver enzymes in your blood. Then, theyll do more blood tests to look for:

# Igm antibodies- Your body makes these when youre first exposed to hepatitis A. They stay in your blood for about 3 to 6 months.

# Igm antibodies- These show up after the virus has been in your body for a while. You may have them all your life. They protect you against hepatitis A. If you test positive for them but not for IgM antibodies, it means you had a hepatitis A infection in the past or had vaccinations to protect against it.

Complications of Hepatitis A?

Treatment of Hepatitis A?

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What Is Hepatitis B

Hepatitis B is an infection of your liver. Itâs caused by a virus. There is a vaccine that protects against it. For some people, hepatitis B is mild and lasts a short time. These âacuteâ cases donât always need treatment. But it can become chronic. If that happens, it can cause scarring of the organ, liver failure, and cancer, and it even can be life-threatening.

Itâs spread when people come in contact with the blood, open sores, or body fluids of someone who has the hepatitis B virus.

It’s serious, but if you get the disease as an adult, it shouldnât last a long time. Your body fights it off within a few months, and youâre immune for the rest of your life. That means you can’t get it again. But if you get it at birth, itâ unlikely to go away.

âHepatitisâ means inflammation of the liver. There are other types of hepatitis. Those caused by viruses also include hepatitis A and hepatitis C.

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