Tuesday, May 17, 2022

What Is The Treatment For Hepatitis C

What Do Hepatitis C Symptoms Look Like

New treatment to cure Hepatitis C

Hepatitis C infection can go through two stages: acute and chronic. In the early, or acute stage, most people don’t have symptoms. If they do develop symptoms, these can include:

  • flu-like symptoms, tiredness, high temperature and aches and pains
  • loss of appetite
  • tummy pain
  • jaundice, meaning your skin and the whites of your eyes turn yellow

While for some people, the infection will clear without treatment, in most cases, acute infection will develop into long-term chronic infection. Chronic infection may not become apparent for a number of years until the liver displays signs of damage. These symptoms can include:

  • mental confusion and depression these are specific to hepatitis C
  • constantly feeling tired
  • nausea, vomiting or tummy pain
  • dark urine
  • feeling bloated
  • joint and muscle pain

Without treatment, chronic hepatitis C can cause scarring of the liver , which can cause the liver to stop working properly. A small number of people with cirrhosis develop liver cancer and these complications can lead to death. Other than a liver transplant, theres no cure for cirrhosis. However, treatments can help relieve some of the symptoms.

Side Effects Of Treatment

Treatments with direct acting antivirals have very few side effects. Most people find DAA tablets very easy to take.

You may feel a little sick and have trouble sleeping to begin with, but this should soon settle down.

Your nurse or doctor should be able to suggest things to help ease any discomfort.

You need to complete the full course of treatment to ensure you clear the hepatitis C virus from your body.

If you have any problems with your medicines, speak to your doctor or nurse straight away.

Side effects for each type of treatment can vary from person to person.

For a very small number of people, more severe side effects from hepatitis C treatments may include:

What Drugs Cure Hepatitis C Infection

    Most hepatitis C is currently treated with all-oral medical regimens of “direct-acting antivirals” or DAAs. DAAs is a term used to distinguish these hepatitis C drugs from an older generation of injected medicines that act indirectly on the immune response to the hepatitis C virus. DAAs act directly on the virus to block different steps in its life cycle. There are several DAAs that are used in combinations that have been scientifically proven to cure hepatitis C. They are not interchangeable, and some are only available combined in one pill or dose pack as a specific combination. DAAs are not used as single-drug therapy because of the high risk of the virus developing resistance and because they work best in combinations. The choice of which regimen to use depends upon the genotype of the virus, the level of liver fibrosis , and any drug resistance that may be present .

    Examples of combination DAAs with cure rates between 91%-100% include:

    • Harvoni
    • Zepatier
    • Mavyret

    Genotype 1a and 1b are the commonest genotypes in the United States. Of all the genotypes, genotype 3 has been the most difficult to treat with DAAs alone and required the use of ribavirin, which has significant side effects. All genotypes can now be treated with oral DAAs without ribavirin. Some genotypes may still require the use of injected pegylated interferon and/or ribavirin if there is no response to DAAs.

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      What Are The Side Effects Of Treatment

      Some people stop therapy because of side effects. Since hepatitis C can lead to liver damage, cirrhosis, and liver cancer if not treated, its vital to stick with a treatment plan.

      Newer drugs have fewer severe side effects than pegylated interferon and ribavirin. Nevertheless, you may feel some effects while taking hepatitis C medication. Side effects can include:

      • nausea, vomiting, or diarrhea
      • appetite loss or weight loss

      Serious side effects can occur with pegylated interferon and ribavirin treatment. If youre taking these medications, you should be monitored for these serious side effects:

      • anemia
      • thrombocytopenia
      • light sensitivity in the eyes
      • trouble breathing because of lung tissue inflammation
      • suicidal thoughts, depression, or irritability
      • thyroid disease
      • elevated liver enzymes
      • autoimmune disease flares

      Some medications arent recommended if theres evidence of liver damage, like cirrhosis . A co-infection with HIV also affects medication options.

      Treatment For Acute Hepatitis C

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      Acute Hepatitis C is a short-term infection which occurs within the first six months of being exposed to the virus. Most people will clear the infection on their own without treatment. If the infection does not clear up, or turns into chronic Hepatitis C, then your healthcare professional may prescribe antivirals.

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      How Can I Protect Myself From Hepatitis C Infection

      If you dont have hepatitis C, you can help protect yourself from hepatitis C infection by

      • not sharing drug needles or other drug materials
      • wearing gloves if you have to touch another persons blood or open sores
      • making sure your tattoo artist or body piercer uses sterile tools and unopened ink
      • not sharing personal items such toothbrushes, razors, or nail clippers

      Hepatitis C can spread from person to person during sex, but the chances are low. People who have multiple sex partners, have HIV or other sexually transmitted diseases, or who engage in rough or anal sex have a higher chance of getting hepatitis C. Talk with your doctor about your risk of getting hepatitis C through sex and about safe sex practices, such as using a latex or polyurethane condom to help prevent the spread of hepatitis C.

      If you had hepatitis C in the past and your body fought off the infection or medicines cured the infection, you can get hepatitis C again. Follow the steps above, and talk with your doctor about how to protect yourself from another hepatitis C infection.

      If you think you may have been exposed to the hepatitis C virus, see your doctor as soon as possible. Early diagnosis and treatment can help prevent liver damage.

      Getting Tested Is The Only Way To Know If You Have Hepatitis C

      A blood test called a hepatitis C antibody test can tell if you have been infected with the hepatitis C viruseither recently or in the past. If you have a positive antibody test, another blood test is needed to tell if you are still infected or if you were infected in the past and cleared the virus on your own.

      • Are 18 years of age and older
      • Are pregnant
      • Currently inject drugs
      • Have ever injected drugs, even if it was just once or many years ago
      • Have HIV
      • Have abnormal liver tests or liver disease
      • Are on hemodialysis

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      Antiviral Medication For Hepatitis C

      For people with hepatitis C, the goal of treatment with antiviral medication is to prevent the virus from replicating, or copying itself, and to eliminate the virus from the bloodstream. If the hepatitis C virus has been in the body for more than six months, the infection is considered chronic. Without treatment, most people with acute hepatitis C develop the chronic form of the disease.

      Your doctor decides which antiviral medicationor combination of medicationsto prescribe based on the results of a blood test called a genotype test. There are six genotypes, or strains, of the hepatitis C virus, and people with certain genotypes respond more quickly to medical treatment.

      For many years, the standard treatment for chronic hepatitis C consisted of the antiviral medications pegylated interferon and ribavirin. Ribavirin is taken by mouth every day, and interferon is an injection that you or a caregiver can administer once a week at home.

      In 2013 and 2014, the U.S. Food and Drug Administration approved a group of new medications for the treatment of hepatitis C. These medications, which include sofosbuvir, are very effective and have fewer side effects than older medications, particularly interferon.

      Can I Drink Alcohol If I Have Hepatitis C

      Universal Hepatitis C Treatment

      The combination of any cause of hepatitis, such as alcohol on top of HCV, adds to and accelerates liver damage. Both hepatitis B and C can cause chronic hepatitis and progression to cirrhosis and liver cancer, although the disease is much more likely to become chronic in the U.S. Therefore, people with chronic HCV should not drink alcohol and should talk to a doctor about vaccines for other hepatitis viruses.

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      What Can People Do To Help The Medications Work Best

      • Take the medications every day
      • Stay in touch with pharmacy to be sure that all refills are ready on time
      • Take the medications exactly as prescribed
      • Do not skip doses
      • Get all blood tests done on time
      • Go to all visits with providers as recommended
      • Tell the provider about all other medications that are being taken – including over-the-counter medicines, vitamins, herbs, and supplements
      • Complete the entire course of medication

      What Are The Treatments For Hepatitis C

      Treatment for hepatitis C is with antiviral medicines. They can cure the disease in most cases.

      If you have acute hepatitis C, your health care provider may wait to see if your infection becomes chronic before starting treatment.

      If your hepatitis C causes cirrhosis, you should see a doctor who specializes in liver diseases. Treatments for health problems related to cirrhosis include medicines, surgery, and other medical procedures. If your hepatitis C leads to liver failure or liver cancer, you may need a liver transplant.

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      Hepatitis C Recurrence: What Are The Risks And Treatment

      Hepatitis C Recurrence is of the various types major division is based on the acute or the chronic. In the later stages of the infection with this virus, the infections stay for the whole lifetime. The studies also suggest that 70-85% of the patients infected with this virus are curable.

      The treatment is better than the previous conditions, and also, the average risk of the occurrence of the disease is less than 1%. But it is also important to take the proper precautions to prevent the occurrence of the disease.

      How Do Doctors Treat Autoimmune Hepatitis

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      Doctors treat autoimmune hepatitis with medicines that suppress, or decrease the activity of, your immune system, reducing your immune systems attack on your liver. The medicines doctors most often prescribe are corticosteroidsprednisone or prednisolonewith or without another medicine called azathioprine.

      Doctors typically start with a relatively high dose of corticosteroids and then gradually lower the dose. Your doctor will try to find the lowest dose that works for you. Your doctor will use blood tests to find out how you are responding to the treatment. A decrease in levels of the liver enzymes alanine transaminase and aspartate transaminase shows a response to treatment. ALT and AST falling to normal levels shows a full response. In some cases, a doctor may repeat a liver biopsy to confirm the response to treatment and find out whether the damage has resolved.

      Treatment can relieve symptoms and prevent or reverse liver damage in many people with autoimmune hepatitis. Early treatment of autoimmune hepatitis can lower the chances of developing cirrhosis and other complications. A minority of people who have no symptoms or only a mild form of the disease may or may not need medicines.

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      Who Is At Risk For Hepatitis C

      You are more likely to get hepatitis C if you

      • Have injected drugs

      If you have chronic hepatitis C, you probably will not have symptoms until it causes complications. This can happen decades after you were infected. For this reason, hepatitis C screening is important, even if you have no symptoms.

      How Do My Healthcare Professional And I Decide On Treatment

      Your healthcare professional will look at your health history and decide if treatment is right for you. The treatment you receive and the length of treatment may depend on:

      • how much virus is in your body
      • your genotype of hep C
      • whether you have liver damage
      • whether or not youve been treated previously

      Next:

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      What Are The Names Of The Medications For Treating Hepatitis C

      Since 2014, multiple different antiviral treatments for hepatitis C have been developed. With the many options now available, often there is more than one good choice for a patient. Some of the treatments are recommended as first-line options, some are second-line options, and others are used less commonly in light of all the available choices.

      • Elbasvir/Grazoprevir

      Second line hepatitis C medications:

      • Sofosbuvir/Velpatasvir/Voxelaprevir

      What Is The Treatment For Hepatitis C In Children

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      When babies acquire an HCV infection through transmission at birth, doctors may monitor and wait until after age 3 to see if the infection goes away without treatment. As many as 40 percent of kids in these cases may clear the hepatitis C virus on their own, according to the American Liver Foundation.

      Antiviral medications used to treat the viral infection are not generally recommended for use in children under 3 years old. Instead, the doctor may simply monitor your child, especially if they remain asymptomatic.

      Older children may take antiviral medications interferon or a combination of interferon with ribavirin for months to years to clear the infection. The specific treatment your child receives will depend on the genotype of the virus and how your child is responding to the medications.

      If the virus does not clear with antiviral therapy, your childs doctor may recommend a liver transplant. However, the need for a liver transplant is extremely rare in children, and theres an increased chance that the new liver may contain the viral infection as well.

      way kids are exposed to the virus. What this means is that a mother who has hepatitis C passes the virus to her unborn child.

      Other ways hepatitis C is transmitted:

      Ways hepatitis C is not transmitted:

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      What About Patients With Hepatitis C Who Also Have Hepatitis B

      Hepatitis B virus can flare in patients who are co-infected with hepatitis B and hepatitis C and are taking medication for hepatitis C. This has been reported as a potential risk for patients who are taking hepatitis C treatment and have underlying hepatitis B as well. The flare usually occurs within a few weeks after the patient starts taking medication for hepatitis C. Therefore, patients who have both hepatitis B and hepatitis C should be seen by a hepatitis expertbeforestarting treatment of the hepatitis C they may need to start taking hepatitis B treatment to avoid a hepatitis B flare.

      How Do Doctors Treat Hepatitis C

      Doctors treat hepatitis C with antiviral medicines that attack the virus and can cure the disease in most cases.

      Several newer medicines, called direct-acting antiviral medicines, have been approved to treat hepatitis C since 2013. Studies show that these medicines can cure chronic hepatitis C in most people with this disease. These medicines can also cure acute hepatitis C. In some cases, doctors recommend waiting to see if an acute infection becomes chronic before starting treatment.

      Your doctor may prescribe one or more of these newer, direct-acting antiviral medicines to treat hepatitis C:

      You may need to take medicines for 8 to 24 weeks to cure hepatitis C. Your doctor will prescribe medicines and recommend a length of treatment based on

      • which hepatitis C genotype you have
      • how much liver damage you have
      • whether you have been treated for hepatitis C in the past

      Your doctor may order blood tests during and after your treatment. Blood tests can show whether the treatment is working. Hepatitis C medicines cure the infection in most people who complete treatment.

      Hepatitis C medicines may cause side effects. Talk with your doctor about the side effects of treatment. Check with your doctor before taking any other prescription or over-the-counter medicines.

      For safety reasons, talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices.

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      Should I Be Screened For Hepatitis C

      Doctors usually recommend one-time screening of all adults ages 18 to 79 for hepatitis C. Screening is testing for a disease in people who have no symptoms. Doctors use blood tests to screen for hepatitis C. Many people who have hepatitis C dont have symptoms and dont know they have hepatitis C. Screening tests can help doctors diagnose and treat hepatitis C before it causes serious health problems.

      Hepatitis C Symptoms & Treatment

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      FAST FACTS:

      • Hepatitis C is found in infected blood. It is also rarely found in semen and vaginal fluids.

      • Hepatitis C is mainly passed on through using contaminated needles and syringes or sharing other items with infected blood on them. It can also be passed on through unprotected sex, especially when blood is present.

      • You can prevent hepatitis C by never sharing needles and syringes, practising safer sex, and avoiding unlicensed tattoo parlours and acupuncturists.

      • Hepatitis C will often not have any noticeable symptoms, but a simple blood test carried out by a healthcare professional will show whether you have hepatitis C.

      • In the early stages, some peoples bodies can clear a hepatitis C infection on their own, others may develop chronic hepatitis C and will need to take antiviral treatment to cure the infection.

      • Without treatment, chronic hepatitis C can lead to permanent liver damage.

      Hepatitis C is part of a group of hepatitis viruses that attack the liver.

      Its mainly passed on through contaminated needles, either from injecting drugs or from needle stick injuries in healthcare settings. It can also be transmitted sexually, especially during anal sex or other types of sex that may involve blood.

      Some groups are more at risk of getting hepatitis C than others, including people who use drugs, people in prisons, men who have sex with men, health workers and people living with HIV.

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