Why Is It So Important To Take Hepatitis C Drugs Correctly
Taking any medicine correctly is extremely important. Taking medicines correctly means:
For hepatitis C drugs, these issues are especially important because, if a medicine is not taken correctly, it may not kill the virus completely. Then, because the virus has “seen” the drug, it learns how to mutate and change in ways that allow it to escape the drug and avoid getting killed off. This is called drug resistance.
Developing drug resistance is a serious issue. It means that the treatment may not work and that the patient may not respond to future treatments.
To prevent drug resistance, it is important to take any medication correctly, but especially DAAs such as Harvoni, Mavyret, Epclusa, and Zepatier.
Resistance can develop quickly. It is very important to take these new antiviral medications according to instructions, on schedule, and not to skip or reduce doses.
Can The Results Of Liver Panel Tests Point To The Presence Of Hepatitis C
A “liver panel” usually includes tests called AST, ALT, bilirubin, alkaline phosphatase, and some others. Abnormal results could show up in many different conditions, not just hepatitis C. And even if the results of a liver panel are normal, you might still have hepatitis C. So, the liver panel alone cannot tell your provider the answer.
Hepatitis C can be diagnosed only by blood tests that are specific to hepatitis C:
In short, if the results of one or more tests on a liver panel are abnormal, generally speaking, the tests should be repeated and confirmed. If the results remain abnormal, your provider should be prompted to look for the cause.
More important than using the liver panel, if you have risks of having been infected with hepatitis C then you should have the specific hepatitis C antibody test to determine if you have hepatitis C infection.
Who Gets Hepatitis C
Who gets hepatitis C?
Anyone can get hepatitis C virus. But unlike a cold or flu virus, HCV isnât easy to catch. The virus is transmitted only by direct contact with human blood that contains the virus. There are several ways infection can occur. Those at risk of being infected with hepatitis C virus include:
What about tattooing?
Several studies have shown there is no link between licensed commercial tattooing parlors and HCV infection, âbut transmission of Hepatitis C is possible when poor infection-control practices are used during tattooing or piercing,â according to the Centers for Disease Control and Prevention .
The agency advises people thinking about getting tattoos or body piercing to consider the health risks. Itâs possible to get infected with HCV, the CDC says, if the tools used have someone elseâs blood on them, or if the piercer or tattoo artist fails to use proper hygiene, such as washing hands, sterilizing tools, and using disposable gloves.
Is it possible to contract HCV from a shared razor or toothbrush?
There are no documented cases of transmission, but the CDC warns that people should not share toothbrushes, razors, or other personal care items: They might have small amounts of infected blood on them.
The CDC stresses that the hepatitis C virus is NOT spread by casual contact or by breast feeding, hugging or kissing, sneezing, coughing, or sharing utensils, drinking glasses, food, or water.
Is sex safe?
References
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What Foods Should I Avoid
Everyone should avoid eating a lot of fat, cholesterol, salt and processed sugar, even if their liver is healthy. In addition, those with HCV should limit or avoid alcohol. Drinking alcohol will speed up liver damage.
Eating properly can help decrease some of the symptoms of Hepatitis C, like feeling tired and sick. Drink lots of water for general health benefits. HCV is not a digestive disease diet will not affect the disease. Your provider may put you on a special diet if you have advanced liver disease.
Hiv And Hepatitis C Coinfection
HCV infection is common among people with HIV who also inject drugs. Nearly 75% of people living with HIV who report a history of injection drug use are co-infected with HCV. All people who are diagnosed with HIV are recommended to be tested for HCV at least once. People living with HIV are at greater risk for complications and death from HCV infection. Fortunately, direct acting antivirals that are used to treat HCV work equally well in people with and without HIV infection. For more information about HIV and HCV coinfection, visit the HIV.govs pages about hepatitis C and HIV coinfection.
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Who Is More Likely To Get Hepatitis C
People more likely to get hepatitis C are those who
- have injected drugs
- had a blood transfusion or organ transplant before July 1992
- have hemophilia and received clotting factor before 1987
- have been on kidney dialysis
- have been in contact with blood or infected needles at work
- have had tattoos or body piercings
- have worked or lived in a prison
- were born to a mother with hepatitis C
- are infected with HIV
- have had more than one sex partner in the last 6 months or have a history of sexually transmitted disease
- are men who have or had sex with men
In the United States, injecting drugs is the most common way that people get hepatitis C.13
What Are The Side Effects Of Drug Treatment
Common side effects for some treatments for hepatitis C may include the following:
- nausea
- fatigue
- depression
Side effects are usually worst during the first few weeks of treatment. They become less severe over time. If you are having trouble dealing with the side effects of your medicine, talk to your doctor. He or she can suggest ways to relieve some of the side effects. For example, if your medicine makes you feel nauseated, it may help to take it right before you go to sleep.
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What Are Genotypes And What Do They Mean
Viruses have genes, too. The genotype of virus you have can be one of six different groups, or genotypes. Most patients with hepatitis C in the United States have genotype 1a or 1b, but in other parts of the world, other genotypes are more common.
There isn’t a “better” or “worse” genotype to have. In the past , genotype 1 was the most difficult to successfully cure but this is no longer the case. All the new direct-acting antiviral medicines work extremely well in treating all genotypes. Sometimes genotype 3 is a little harder to cure, but in general, all genotypes now have extremely high likelihoods of being cured with hepatitis C treatment.
How To Prevent Hepatitis C
There is currently no vaccine for hepatitis C. Avoiding contact with infected blood is the only way to prevent the condition.
The most common way for people to contract hepatitis C is by injecting street drugs. Because of this, the best way to prevent hepatitis C is to avoid injecting.
Treatments can help many people quit. People in the U.S. can call the National Helpline for help with finding treatments.
If a person finds it difficult to stop, they can reduce the risk of contracting hepatitis C by never sharing drug equipment, ensuring a clean, hygienic environment, and always using new equipment, including syringes, ties, alcohol swabs, cottons, and cookers.
People who may come into contact with infected blood, such as healthcare workers and caretakers, should always wash the hands thoroughly with soap and water after any contact, or suspected contact, with blood. They should also wear gloves when touching another persons blood or open wounds.
People can also reduce their risk by making sure that any tattoo artist or body piercer they visit uses fresh, sterile needles and unopened ink.
The risk of contracting hepatitis C through sexual contact is low. Using barrier protection, such as condoms, reduces the risk of most sexually transmitted infections.
People who have hepatitis C can reduce the risk of transmitting it to others by:
There are many misconceptions about how hepatitis C spreads. People cannot transmit or contract the virus through:
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Why Should I Get Treated
Hepatitis C can be fatal when left untreated.
Untreated hepatitis C can lead to scarring of the liver known as cirrhosis.
A small number of people with cirrhosis will go on to get liver failure, the only treatment for which is a liver transplant. A small proportion of people with cirrhosis develop liver cancer.
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Tests For Liver Problems
To check how well your liver is working, you may have:
- Liver function tests. These are blood tests that can help your doctor find out if you have liver damage.
- A liver biopsy. The doctor puts a needle in the liver to find out whether the virus has caused scarring or damage to your liver.
- Imaging tests such as a CT scan, an MRI, or an ultrasound to make sure that you dont have liver cancer.
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Finding A Hep C Specialist
Hep C treatments can be prescribed by many different Hep C Specialists, including gastroenterologists, general practitioners, nurse practitioners, and addiction medicine specialists.
To find a Hep C Specialist near you, enter your city and state or ZIP code.
-
Gastroenterologists
A gastroenterologist is a doctor who specializes in the treatment of diseases that affect the digestive system.
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Hepatologists
A hepatologist is a doctor who specializes in the treatment of diseases that affect the liver.
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Other Specialists
Other specialists who treat Hep C may include, but are not limited to, infectious disease specialists, primry care physicians , internal medicine specialists , family doctors, nurse practitioners , and physician assistants .
Hepatitis C Antibody Test
Certain foreign substances that enter your body trigger your immune system to make antibodies. Antibodies are specifically programmed to only target the foreign substance they were made to fight.
If youve ever had a hepatitis C infection, your body will make hepatitis C antibodies as part of its immune response.
Your body only makes these antibodies if you have hepatitis C or had it in the past. So the hepatitis C antibody test can confirm whether you have the virus by testing for these specific antibodies.
It may take 2 to 3 months after exposure for the test to detect antibodies. If needed, your healthcare professional may order an HCV RNA test, which can detect the virus after just 1 or 2 weeks.
If the antibody test is positive, an HCV RNA test can show whether the infection is current.
While people of any gender experience the same hepatitis C symptoms, 2014 research suggested some effects of the virus may differ, depending on the sex you were assigned at birth.
Researchers noted that:
- women have a higher chance of clearing the virus without treatment
- liver disease may progress more rapidly in men
- men have a higher chance of developing cirrhosis
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How To Avoid Spreading Hepatitis C
- Tell the people that you live with or have sex with about your illness as soon as you can.
- Donât share needles to inject drugs. Donât share other equipment with others. Find out if a needle exchange program is available in your area, and use it. Get into a drug treatment program.
- Practice safer sex. Reduce your number of sex partners if you have more than one. Unless you are in a long-term relationship in which neither partner has sex with anyone else, always use latex condoms when you have sex.
- Donât donate blood or blood products, organs, semen, or eggs .
- Make sure that all equipment is sterilized if you get a tattoo, have your body pierced, or have acupuncture.
- Do not share your personal items. These include razors, toothbrushes, towels, and nail files.
- Tell your doctor, dentist, and anyone else who may come in contact with your blood about your illness.
- Prevent others from coming in contact with your blood and other body fluids. Keep any cuts, scrapes, or blisters covered.
- Wash your handsâand any object that has come in contact with your bloodâthoroughly with water and soap.
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What Are The Treatment Guidelines For Hepatitis C
Hepatitis C treatment is best discussed with a doctor or specialist familiar with current and developing options as this field is changing, and even major guidelines may become outdated quickly.
The latest treatment guidelines by the American Association for the Study of Liver Disease and Infectious Disease Society of America recommends use of DAAs as first-line treatment for hepatitis C infection. The choice of DAA varies by specific virus genotype, and the presence or absence of cirrhosis. In the U.S., specific insurance providers also might influence the choice due to the high cost of DAAs. Although the individual, public health, and cost benefits of treating all patients with hepatitis C is clear, the most difficult barrier to treating all people with HCV is the very high cost of the drug regimens. Patients are encouraged to discuss options with their health care professional.
Treatment is recommended in all patients with chronic hepatitis C unless they have a short life expectancy that is not related to liver disease. Severe life-threatening liver disease may require liver transplantation. Newer therapies with DAAs have allowed more and more patients to be treated.
What are the goals of therapy for hepatitis C infection?
The ultimate goals of antiviral therapy are to
- prevent transmission of hepatitis C,
- prevent progression to cirrhosis and liver cancer, and
- improve survival and quality of life.
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How Do Doctors Treat Hepatitis C
Doctors treat hepatitis C with antiviral medicines that attack the virus and can cure the disease in most cases.
Several newer medicines, called direct-acting antiviral medicines, have been approved to treat hepatitis C since 2013. Studies show that these medicines can cure chronic hepatitis C in most people with this disease. These medicines can also cure acute hepatitis C. In some cases, doctors recommend waiting to see if an acute infection becomes chronic before starting treatment.
Your doctor may prescribe one or more of these newer, direct-acting antiviral medicines to treat hepatitis C:
You may need to take medicines for 8 to 24 weeks to cure hepatitis C. Your doctor will prescribe medicines and recommend a length of treatment based on
- which hepatitis C genotype you have
- how much liver damage you have
- whether you have been treated for hepatitis C in the past
Your doctor may order blood tests during and after your treatment. Blood tests can show whether the treatment is working. Hepatitis C medicines cure the infection in most people who complete treatment.
Hepatitis C medicines may cause side effects. Talk with your doctor about the side effects of treatment. Check with your doctor before taking any other prescription or over-the-counter medicines.
For safety reasons, talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices.
Sharing Toothbrushes Scissors And Razors
There’s a potential risk that hepatitis C may be passed on through sharing items such as toothbrushes, razors and scissors, as they can become contaminated with infected blood.
Equipment used by hairdressers, such as scissors and clippers, can pose a risk if it has been contaminated with infected blood and not sterilised or cleaned between customers. However, most salons operate to high standards, so this risk is low.
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How To Prevent Hepatitis B
Hepatitis B is a liver infection caused by a virus . It can be serious and theres no cure, but the good news is its easy to prevent. You can protect yourself by getting the hepatitis B vaccine and having safer sex. If you have oral, anal, and vaginal sex, use condoms and dental dams to help stop the spread of hepatitis B and other STDs.
How Can You Prevent Hepatitis B And Hepatitis C
Hepatitis B: Vaccination is the best way to prevent all of the ways that hepatitis B is transmitted. People with HIV who do not have active HBV infection should be vaccinated against it. In addition to the 3-dose series of hepatitis B vaccine given over 6 months, as of 2017, there is a 2-dose series given over 1 month.
Hepatitis C: No vaccine exists for HCV and no effective pre- or postexposure prophylaxis is available. The best way to prevent hepatitis C infection is to never inject drugs or to stop injecting drugs by getting into and staying in drug treatment. If you continue injecting drugs, always use new, sterile needles or syringes, and never reuse or share needles or syringes, water, or other drug preparation equipment.
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Tests To Diagnose Hepatitis C
How is Hepatitis C diagnosed?
There are two main blood tests typically used to diagnose Hepatitis C. First, youll have a screening test that shows if youve ever had Hepatitis C at some point in your life. If this test is positive, youll have a second test to see if you have Hepatitis C now. These blood tests are described below:
Hepatitis C antibody test
This is the screening test used by doctors to show whether or not you have ever been exposed to Hepatitis C at some time in your life, by detecting antibodies in your blood. Antibodies are substances your body makes to fight off all kinds of infections. If you were ever infected with Hepatitis C, your body would have made antibodies to fight the virus.
If the test result is:
- Negative, it means you have not been exposed to Hepatitis C and further testing is usually not needed.
- Positive, you have had Hepatitis C at some point. However, it does not tell you whether you have it now. Youll need to see your doctor for another test the Hepatitis C RNA test to determine if the virus is still active and present in your blood.
Hepatitis C RNA Qualitative Test
This test will determine whether or not you are currently infected with Hepatitis C. It is often called the PCR test because of the process used . It looks for the genetic material of the Hepatitis C virus in your blood.
If the test result is:
Hepatitis C RNA Quantitative Test