Is There A Cure
Though there is no vaccine for Hepatitis C, treatments can reduce the viral load to undetectable levels which is considered cured or in remission.
The virus is considered cured when it is not detected in your blood 12 weeks after treatment is completed. This is otherwise known as a sustained virologic response .
Hepatitis C is one of the most serious hepatitis viruses. However, with newer treatments developed over the past few years, the virus is much more manageable than it was in the past.
Current antiviral drugs that help cure hepatitis C may also help prevent the health complications of chronic liver disease.
The reports less than half of people who contract the hepatitis C virus may clear it from their bodies without treatment. For this group of people, the virus will be a short-term acute condition that goes away without treatment.
But for most people, acute hepatitis C will likely develop into a chronic condition that requires treatment.
Since the virus often doesnt produce symptoms until after more significant liver damage occurs, its important to get tested for hepatitis C if you think you might have been exposed.
approved the antiviral drug Mavyret for an 8-week treatment period for people with all genotypes of hepatitis C.
This treatment is now being used for many people instead of the 12-week treatment that was previously required.
Noninvasive ways to test for liver damage caused by hepatitis C are also now available to aid in diagnosis.
Youve Lost The Hepatitis B Surface Antigen Go Celebrate But Keep Monitoring
After years of living with inactive chronic hepatitis Bwith low viral load and no signs of liver damagesome patients may finally lose the hepatitis B surface antigen and even develop surface antibodies.
This event merits a celebration and a huge sigh of relief, but if you think you will never have to get another blood draw or worry about your liver, think again. We hate to be the bearer of bad news, but hepatitis B really never goes away.
Think herpes, mono, or chicken pox and shingles. Children infected with chickenpox get rid of the infection and the ugly blisters, but very small amounts of the chickenpox virus remains in the spinal nerves. As we grow older and our immune systems weaken with age, our bodies arent able to suppress the varicella virus any more and it reactivates, causing painful shingles.
The hepatitis B virus behaves in the same way. When we lose HBsAg and even develop surface antibodies , there are still HBV lurking in our livers. When were healthy, our immune systems suppress the virus and prevent any reactivation, but old age or another disease or medical condition can weaken our bodies and allow the viral infection to reactivate.
So, even after we clear HBsAg, we need to stay vigilant and continue to get our liver health monitored regularly. Here is what you need to know:
- Check all of your liver enzymes and liver function
- Get your platelet count and hepatitis B blood tests done, and
- Have an ultrasound of your liver and spleen.
Hepatitis B And Pregnancy
If youâre pregnant, you might pass the virus to your baby at birth. Itâs less likely to happen during your pregnancy.
If your baby gets the virus and isnât treated, they could have long-term liver problems. All newborns with infected mothers should get hepatitis B immune globulin and the vaccine for hepatitis at birth and during their first year of life.
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How Do I Get Hepatitis B Treatment
Usually for adults, hepatitis B goes away on its own and you wont need treatment. Your doctor might tell you to rest, eat well, and get plenty of fluids. You may also get medicines to help with any symptoms you might have but be sure to talk with your doctor or nurse before taking anything.
If you have chronic hepatitis, there are medicines you can take to treat it. Your doctor will tell you about your options and help you get whatever treatment you need.
Is Surgery A Treatment For Hepatitis B
There is no surgical therapy for hepatitis B.
If liver damage is so severe that the liver starts to fail, liver transplant may be recommended:
- Liver transplant is a major process and surgery with an extended recovery period.
- It also depends on the availability of a matching donor liver.
- If liver transplant becomes a possibility for an individual, a health care practitioner will discuss the risks and benefits with them.
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Should I Be Screened For Hepatitis B
Screening is testing for a disease in people who have no symptoms. Doctors use blood tests to screen for hepatitis B. Many people who have hepatitis B dont have symptoms and dont know they are infected with hepatitis B. Screening tests can help doctors diagnose and treat hepatitis B, which can lower your chances of developing serious health problems.
Your doctor may recommend screening for hepatitis B if you9,14
- are pregnant
- were born in an area of the world where 2 percent or more of the population has hepatitis B infection, which includes Africa, Asia, and parts of the Middle East, Eastern Europe, and South America
- didnt receive the hepatitis B vaccine as an infant and have parents who were born in an area where 8 percent or more of the population had hepatitis B infection, which includes sub-Saharan Africa and parts of Asia
- are HIV-positive
- are a man who has sex with men
- have lived with or had sex with a person who has hepatitis B
- have an increased chance of infection due to other factors
What You Can Do
Here’s some information to help you get ready for your appointment.
- Be aware of pre-appointment restrictions. When you make the appointment, ask if there’s anything you need to do in advance, such as restrict your diet.
- Write down your symptoms, including any that may seem unrelated to the reason for which you scheduled the appointment.
- Write down key personal information, including major stresses or recent life changes.
- Make a list of all medications, vitamins and supplements you take.
- Consider taking a family member or friend along. Someone who accompanies you may help you remember the information you receive.
- Write down questions to ask your doctor.
Listing questions for your doctor can help you make the most of your time together. For hepatitis B infection, some basic questions to ask your doctor include:
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Can A Transplant Cure Hepatitis C
If you develop chronic hepatitis C and it leads to liver cancer or liver failure, you may need a liver transplant. Hepatitis C is one of the most common reasons for a liver transplant.
A liver transplant removes a damaged liver and replaces it with a healthy one. However, theres a high likelihood that the hepatitis C virus will be transmitted to the new liver in time.
The virus lives in your bloodstream, not just your liver. Removing your liver wont cure the disease.
If you have active hepatitis C, continued damage to your new liver is very likely, especially if hepatitis C remains untreated.
Other Body Fluids And Tissues
Hepatitis B is found in semen and vaginal secretions. The virus can be transmitted during unprotected sexual intercourse, and from mother to infant during birth.
Synovial fluid , amniotic fluid, cerebrospinal fluid, and peritoneal fluid can contain the hepatitis B virus, but the risk of transmission to workers is not known.
Feces, nasal secretions, sputum, sweat, tears, urine, and vomit have not been implicated in the spread of hepatitis B. Unless they are visibly contaminated with blood, the risk of contracting hepatitis B from these fluids in the workplace is very low.
Hepatitis B is not transmitted by casual contact. For example, hospital employees who have no contact with blood, blood products, or blood-contaminated fluids are at no greater risk than the general public. However, the virus can spread through intimate contact with carriers in a household setting, possibly because of frequent physical contact with small cuts or skin rashes. The virus can also spread through biting and possibly by the sharing of toothbrushes or razors. It is not spread through sneezing, coughing, hand holding, hugging, kissing, breastfeeding, sharing eating utensils, water or food.
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What Are The Signs And Symptoms Of Hepatitis B
You may have no signs or symptoms and may not know you have been infected. Symptoms of an HBV infection can take 1 to 6 months to develop. You may have any of the following:
- Dark urine or pale bowel movements
- Fatigue and weakness
- Loss of appetite, nausea, and vomiting
- Jaundice , itchy skin, or skin rash
- Joint pain and body aches
- Pain in the right upper side of your abdomen
Extrahepatic Replication Of Hbv And Its Role In Hbv Reactivation
Numerous reports demonstrated the presence of HBV DNA, virus genome replicative intermediates and viral proteins in hepatic tissue, and HBV DNA and HBsAg in serum of HBV-infected persons, but the existence of extrahepatic sites of HBV replication are not as well recognized. Nonetheless, the accumulated data indicate that PBMC and different immune cell types can support HBV replication. Stronger evidence came from the woodchuck model of HBV infection. There are also occasional observations that endothelial cells, epithelial cells, neurons, macrophages and polymorphonuclear leukocytes could be permissive to HBV infection in humans. HBV replication was also demonstrated in in vitro bone marrow cultures and lymphatic tissues of patients with CHB. In the woodchuck model of hepatitis B, extrahepatic replication of the woodchuck hepatitis virus and infectivity of the virus derived from lymphoid cells were clearly delineated. Interestingly, in some situations, the lymphatic system might be the only site of virus replication in this model.
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Diagnosis Of Hepatitis B
Blood tests are available to determine if you are or have been infected with hepatitis B. It may take 6 months from the time of infection before a blood test can detect antibodies to hepatitis B, so follow-up testing may be required. During this 6-month period, until you know whether you are infected or not, take action to prevent potential infection of other people.
There are also tests that can assess liver damage from hepatitis B. The interpretation of these tests can be complicated and specialist advice is needed, so talk to your doctor.
All pregnant women are tested for hepatitis B. If you are found to have chronic hepatitis B, your doctor can help reduce the risk of transferring the infection to your newborn child.
How Long Does It Last
According to the World Health Organization , the complete vaccine series induces protective antibody levels in of the infants, children, and adolescents who receive it.
Immune memory induced by the HBV vaccine can last for in healthy people. That said, studies into the duration of the protection that the vaccine offers are ongoing.
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Can Hepatitis B Be Prevented Or Avoided
The best way to prevent hepatitis B is to always have protected sex and, if you use intravenous drugs, avoid sharing needles.
A vaccine is available to prevent hepatitis B. It is now routinely given in the first year of life to all newborn infants. It is safe and requires 3 shots over a 6-month period. This vaccine should be given to people who are at high risk for this illness, such as healthcare workers, all children, people who travel to areas where the infection is widespread, drug users, and those who have multiple sex partners.
What Is The Follow
If an individual has acute hepatitis B, a health care practitioner will draw blood and examine the person periodically to see if the infection is resolving. If the person develops chronic hepatitis B, they will need periodic examinations and blood tests on an ongoing basis. If these tests indicate that the virus is actively damaging the liver, the healthcare practitioner may suggest a liver biopsy or begin antiviral therapy. The individual will also be given a vaccine against hepatitis A, which is an unrelated virus that may cause severe liver disease in people who already carry hepatitis B.
Chronic hepatitis B is associated with hepatocellular carcinoma. Fortunately, this is rare cancer. A blood test can be used to detect a marker for this cancer, or cancer can be detected by abdominal ultrasound. Persons with chronic hepatitis B are usually screened periodically for hepatocellular carcinoma, although it is not clear if this screening improves survival.
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What Should You Know About Pregnancy And Hepatitis B
A pregnant woman who has hepatitis B can pass the infection to her baby at delivery. This is true for both vaginal and cesarean deliveries.
You should ask your healthcare provider to test you for hepatitis B when you find out you are pregnant. However, while it is important for you and your healthcare provider to know if you do have hepatitis B, the condition should not affect the way that your pregnancy progresses.
If you do test positive, your provider may suggest that you contact another healthcare provider, a liver doctor, who is skilled in managing people with hepatitis B infections. You may have a high viral load and may need treatment during the last 3 months of your pregnancy. A viral load is the term for how much of the infection you have inside of you.
You can prevent your infant from getting hepatitis B infection by making sure that your baby gets the hepatitis B vaccine in the hours after they are born along with the hepatitis B immunoglobulin. These two shots are given in two different locations on the baby. They are the first shots needed.
Depending on the type of vaccine used, two or three more doses must be given, usually when the baby is 1 month old and then 6 months old, with the last by the time the baby is 1 year old. It is critical that all newborns get the hepatitis B vaccination, but even more important if you have hepatitis B yourself.
How Do Doctors Treat Hepatitis B
Doctors typically dont treat hepatitis B unless it becomes chronic. Doctors may treat chronic hepatitis B with antiviral medicines that attack the virus.
Not everyone with chronic hepatitis B needs treatment. If blood tests show that hepatitis B could be damaging a persons liver, a doctor may prescribe antiviral medicines to lower the chances of liver damage and complications.
Medicines that you take by mouth include
A medicine that doctors can give as a shot is peginterferon alfa-2a .
The length of treatment varies. Hepatitis B medicines may cause side effects. Talk with your doctor about the side effects of treatment. Tell your doctor before taking any other prescription or over-the-counter medicines.
For safety reasons, you also should talk with your doctor before using dietary supplements, such as vitamins, or any complementary or alternative medicines or medical practices.
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Immunisation For Hepatitis B
Immunisation is the best protection against hepatitis B infection. A course of vaccination is recommended for all babies and people in high-risk groups.
Immunisation can be with a vaccine against hepatitis B alone or with a combination vaccine. To be immunised, contact your doctor or local council.
Protection against hepatitis B is available free of charge under the National Immunisation Program Schedule. In Victoria, immunisation against hepatitis B is free for:
- Babies at birth immunisation against hepatitis B alone as soon as possible after birth.
- Babies at 2, 4 and 6 months combination immunisation in the form of a diphtheria, tetanus, whooping cough, hepatitis B, polio and Haemophilus influenzae type b vaccine .
- Premature babies at 12 months premature babies born under 32 weeks gestation or under 2,000g birth weight receive a single booster dose.
- Children up to and including 9 years of age.
- People aged less than 20 years having a catch-up immunisation.
- Refugees and humanitarian entrants aged 20 years and above.
In Victoria, free hepatitis B vaccine is provided for people who are at increased risk of infection, including:
Immunisation is also recommended, but not necessarily free, for people who are at increased risk of infection, including:
What Is Chronic Hepatitis B
Doctors refer to hepatitis B infections as either acute or chronic:
- An acute HBV infection is a short-term illness that clears within 6 months of when a person is exposed to the virus.
- A person who still has HBV after 6 months is said to have a chronic hepatitis B infection. This is a long-term illness, meaning the virus stays in the body and causes lifelong illness. An estimated 850,000 to more than 2 million people in the U.S. have chronic HBV.
The younger someone is when infected, the greater the chances for chronic hepatitis B.
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Is There A Cure For Chronic Hepatitis B
Currently, there is no complete cure for hepatitis B. But when managed properly, those living with the virus can expect to live a normal life. Maintaining a healthy diet and avoiding alcoholic beverages and tobacco products are crucial components in managing the disease.
You should also visit a doctor familiar with hepatitis B at least annuallythough twice a year might be best to monitor your liver through blood tests and medical imaging. As with most diseases, detecting it early leads to a better outcome. If youre exposed to the virus, you should get an antibody injection within 12 hours of exposure.
What Are The Risk Factors For Getting Hepatitis B
Due to the way that hepatitis B spreads, people most at risk for getting infected include:
- Children whose mothers have been infected with hepatitis B.
- Children who have been adopted from countries with high rates of hepatitis B infection.
- People who have unprotected sex and/or have been diagnosed with a sexually transmitted infection.
- People who live with or work in an institutional setting, such as prisons or group homes.
- Healthcare providers and first responders.
- People who share needles or syringes.
- People who live in close quarters with a person with chronic hepatitis B infection.
- People who are on dialysis.
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