Acute Vs Chronic Infection
Doctors distinguish between chronic and acute infection with hepatitis viruses. Acute infection is a short-term condition, lasting under six months. Chronic infection is a long-term condition, lasting more than six months.
Hepatitis B infection can be either acute or chronic. Most people who get acute hepatitis B dont end up progressing to chronic hepatitis B. By contrast, acute hepatitis C tends to develop into chronic hepatitis C. Approximately 7585 percent of adults newly infected with hepatitis C develop a chronic infection, according to the CDC . Others clear the infection.
When you get acute hepatitis C you may or may not have symptoms. Most cases of acute hepatitis C are asymptomatic, meaning people dont notice the symptoms. Symptoms are only noticeable in 15 percent of cases of acute hepatitis C.
Can Hepatitis Be Treated
Michael says, Now we have more options which are better for the patient and more affordable.
Each form of hepatitis has its method of treatment. Once you know what type of hepatitis you have, you can expect the following treatment process:
- Hepatitis A is a short-term illness that responds well to bed rest, hydration, and nutrition.
- Hepatitis B in its acute form doesnt require treatment but the chronic form of the disease is treated with antiviral medications.
- Hepatitis C is also treated with antiviral medication for both the acute and chronic forms of the disease.
- Hepatitis D doesnt have a very effective treatment regimen at this time there is a medication available but it has low efficacy.
- Hepatitis E usually resolves on its own as a short-term illness.
For prevention, there is a vaccine available to target hepatitis A and hepatitis B. You can also prevent hepatitis D by getting the hepatitis B vaccine. If you believe you have symptoms of hepatitis please call Gastroenterology Associates of Southwest Florida, PA for an appointment at 239-275-8882.
How To Protect Yourself Against Hepatitis C
Unfortunately, there is no vaccine available for hepatitis C, but you can protect yourself by avoiding behaviors such as sharing needles and syringes. In addition, the CDC recommends people born between 1945 and 1965 get tested for hepatitis C. Testing is also recommended for people who were treated for blood-clotting problems before 1987 and recipients of blood transfusions or donated organs before 1992.
The UNC Liver Center has a clinic in Chapel Hill that specializes in hepatitis B and C, incorporating the latest clinical trials and most up-to-date therapies. Treatment for hepatitis is also available at our locations in Asheville, High Point, Raleigh and Wilmington. To learn more, call 966-2516.
Michael Fried, MD, is the director of the UNC Liver Center and a professor of medicine at the UNC School of Medicine.
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Whats The Difference Between Hepatitis A B And C
Infectious Diseases, Liver Health
Youve probably seen stories in the news about hepatitis A outbreaks linked to infected restaurant workers, or how a rising rate of hepatitis C infections is causing increased health care costs.
But you might not know the difference between hepatitis A, B and C, or why you should be concerned about them.
Heres why: Hepatitis, or inflammation of the liver, affects more than 50,000 new people each year and is a leading cause of liver cancer and liver transplants. The Centers for Disease Control and Prevention estimates as many as 6 million people in the U.S. are living with hepatitis.
Having hepatitis can be dangerous and uncomfortable. Symptoms are similar for hepatitis A, B and C and may include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, gray-colored stools, joint pain and jaundice . Even worse, chronic hepatitis often has no symptoms, and people dont know theyre infected until they get very sick.
Michael Fried, MD, director of the UNC Liver Center, explains the difference between the types of hepatitis and how to protect yourself.
Treatment For Hepatitis C Disease
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How Are Hepatitis B And C Diagnosed
Hepatitis B is diagnosed by a series of blood tests. The test may show an ongoing infection or antibodies that indicate that the patient is protected against hepatitis B. In patients who have a positive screening test that suggests the possibility of ongoing infection, further testing is done to determine the levels of the virus in the bloodstream.
Hepatitis C is diagnosed via a blood test called a Hepatitis C Antibody Test. A positive result means that hepatitis C antibodies are present in the blood. But a positive antibody test doesnt necessarily mean a person has hepatitis C. A further blood test is needed to confirm the diagnosis. This second blood test quantifies the amount of the virus or the viral load in the liver and the bloodstream.
How Are Hepatitis B And C Treated
Hepatitis B: Not all patients with chronic hepatitis B infection require treatment. At Yale Medicine, specialists decide on an individual basis whether a patient is an appropriate candidate for treatment. Generally, patients require treatment when their hepatitis B virus level is high, and when laboratory tests demonstrate significant inflammation or injury to the liver.
There are currently seven approved drugs for hepatitis B, two of which are considered to be first-line treatments. These drugs are oral pills taken once daily, and while they’re very effective at suppressing the virus to very low or undetectable levels over the long term, they are not considered curative.
Therefore, the goal of treatment is to control the virus long-term and decrease the risk of hepatitis B related complications such as cirrhosis and liver cancer.
Hepatitis C: For the greater part of the last 20 years, treatment of hepatitis C required the use of a chemotherapy-like injection drug called interferon, which has been associated with serious side effects and a low cure rate. Fortunately, advances in hepatitis C treatments within the last three years now allow for the use of oral medications that are significant improvements in terms of safety and effectiveness.
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Is Hepatitis Testing Recommended For People With Hiv
Yes. Everyone with HIV should be tested for HBV and HCV when they are first diagnosed with HIV and begin treatment. People with HIV who have ongoing risk factors for getting hepatitis B or hepatitis C should be tested annually.
In addition, HCV screening recommendations from the Centers for Disease Control and Prevention call for:
- One-time screening for all adults 18 years and older
- Screening of all pregnant women during every pregnancy
- Testing for all persons with risk factors, with testing continued periodic testing those with ongoing risk.
What Is Viral Hepatitis
Hepatitis means inflammation of the liver. The liver is a vital organ that processes nutrients, filters the blood, and fights infections. When the liver is inflamed or damaged, its function can be affected. Heavy alcohol use, toxins, some medications, and certain medical conditions can cause hepatitis. However, hepatitis is often caused by a virus. In the United States, the most common types of viral hepatitis are hepatitis A, hepatitis B, and hepatitis C.
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Treatment For Hepatitis A Disease
How Do You Get Hepatitis C
Hepatitis C can be contracted only through direct blood contact. In the U.S., the primary mode of transmission is blood exposure through sharing needles. Mother-to-child transmission is about 5 percent of cases. Hepatitis C infection might also be a risk for people who received a blood transfusion or an organ transplant before 1992, when widespread testing of the blood supply for hepatitis C began.
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You Might Not Know You Have It
Nearly half of people living with hepatitis C dont know they have it. Thats because most people live with the disease for years without feeling sick, or experiencing only minor symptoms such as fatigue. Frequently, the only indication of hepatitis C is an abnormal liver blood test panel. If you think you have been exposed to hepatitis C, be sure to talk to your physician.
Finding Help For Hepatitis
If youve been diagnosed with viral hepatitis, there are a variety of resources that are available to help you. Lets explore a few of them below:
- Your doctor. Your doctor is a great first point of contact for questions and concerns. They can help you to better understand the type of hepatitis you have, as well as how it will be treated.
- American Liver Foundation . ALF is dedicated to ending liver disease through education, research, and advocacy. Their site has educational material about viral hepatitis, as well as ways to find doctors, support groups, and clinical trials in your area.
- Patient assistance programs. If you have hepatitis C, the cost of antiviral drugs can be high. The good news is that many drug manufacturers have patient assistance programs that can help you pay for these medications.
The chart below is an at-a-glance summary of some of the key differences between hepatitis A, B, and C.
| Hepatitis A |
|---|
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What Is The Outlook
Most people with hepatitis A recover without any complications. Once youve had hepatitis A, you cant get it again. Antibodies to the virus will protect you for life.
Some people may be at an increased risk for serious illness from hepatitis A. These include:
acute hepatitis B infections in the United States in 2018.
Hepatitis A B And C: What Is The Difference
A, B, C D and E.
Aside from the letters associated with it, how much do you know about hepatitis? Whats the difference between the types? And if you get a vaccination for hepatitis, which are you protected from?
We spoke with Moises Ilan Nevah, MD, a transplant hepatologist/gastroenterologist and medical director of the Liver Transplant Program at Banner University Medical Center Phoenix, to help better understand the similarities and differences between the various types of hepatitis, who is at risk and when to get vaccinated.
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There Is A Test For Hepatitis C
The hepatitis C antibody test determines if a person has been infected with the virus. A positive, or reactive result, means antibodies were found and you were infected with the hepatitis C virus at some point in time. Additional tests are required to confirm if you have active infection at present.
How Is The Hepatitis C Virus Transmitted
The following actions transmit the hepatitis C virus:
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What Are The Types Of Hepatitis
The three most common types of hepatitis in the United States are A, B, and C, but there are five types in total. All of these forms of hepatitis target the livers ability to function. Here are the differences between them:
- Hepatitis A is caused by the hepatitis A virus, which spreads through the blood and stool of people infected by the virus.
- Hepatitis B is also caused by a virus spread through bodily fluids from an infected person however, it can be prevented through the use of vaccines.
- Hepatitis C is also a viral form of hepatitis. It can be short-term or long-term. As a chronic infection, it can cause life-threatening health issues like cirrhosis or liver cancer.
- Hepatitis D, also known as delta hepatitis, only occurs concurrently within people who also have the hepatitis B virus.
- Hepatitis E,though not particularly common in the United States, can spread from eating raw or undercooked pork, shellfish, or wild game.
How Does It Affect The Body
The incubation period for hepatitis B can range from . However, not everyone who has acute hepatitis B will experience symptoms.
About 95 percent of adults completely recover from hepatitis B. However, hepatitis B can also become chronic.
The risk of chronic hepatitis B is greatest in those who were exposed to HBV as young children. Many people with chronic hepatitis B dont have symptoms until significant liver damage has occurred.
In some people whove had hepatitis B, the virus can reactivate later on. When this happens, symptoms and liver damage may occur. People with a weakened immune system and those being treated for hepatitis C are at a higher risk for HBV reactivation.
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How Can You Prevent Hepatitis B And Hepatitis C
Hepatitis B: Vaccination is the best way to prevent all the ways that hepatitis B is transmitted. People with HIV who do not have active HBV infection should be vaccinated against it. The hepatitis B vaccine is now recommended for all infants, children and adults ages 19-59, as well as adults ages 60+ at high risk for infection. There is a 3-dose series of hepatitis B vaccine given over 6 months, and a 2-dose series given over 1 month. Additionally, there is a 2-dose combination vaccine that protects against both hepatitis A and hepatitis B.
Hepatitis C: No vaccine exists for HCV and no effective pre- or post-exposure prophylaxis is available. Injection drug use is one of the risk factors for hepatitis C. For people who inject drugs, the best way to prevent hepatitis C infection is to always use new, sterile needles or syringes, and never reuse or share needles or syringes, water, or other drug preparation equipment. Community-based prevention programs, such as medication-assisted treatment and syringe services programs provide support and services aimed at preventing and reducing the transmission of HCV. Although the risk of sexual transmission of HCV is considered to be low, avoiding unprotected sexual exposure by using condoms has been shown to reduce the chance of sexually transmitted infections.
Is Hepatitis B Worse Than Hepatitis C
Michael says, At the end of the day, its not which ones worsetheyre both bad. He points out that both can lead to liver cancer if left untreated.
Together, hepatitis B and C account for more than 80% of all liver cancers in the world. However, hepatitis B does seem to be more dangerous in some ways than hepatitis C for several reasons:
- Hepatitis B is certainly more virulent and contagious than hepatitis C.
- Hepatitis B is prevalent around the world and it causes more liver cancer than hepatitis C.
- People with hepatitis B are more likely to die from complications to their liver than people with any of the other hepatitis infections.
When comparing hepatitis B and C, we should note that these viruses attack our cells in completely different ways. Hepatitis C operates in the standard virus way, by invading our cells and reproducing copy after copy of itself until it overwhelms the healthy cells. Hepatitis B, however, goes beyond cloning itself to reproduce and instead inserts itself into the healthy cells DNA. This is a more ominous process because it is much harder to destroy the hepatitis B cell when it takes root at the DNA level.
Additionally, hepatitis C typically causes cirrhosis, which is scarring of the liver that interferes with its function, leading to liver cancer. However, in some cases, hepatitis B can cause liver cancer without any signs of cirrhosis. That can make liver cancer itself difficult to diagnose.
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How To Prevent Hepatitis A Disease
The following measures can prevent the hepatitis A virus from entering the body:
Risk Of Hcc Development
2.2.1. Hepatitis B
2.2.1.1. Modes of transmission and Genotype Variation
HBV is typically transmitted vertically, i.e. from mother to newborn or among siblings at younger ages in endemic areas such as Asia and Africa. In low-risk areas, horizontal transmission, i.e. via sexual and parenteral routes, is more the norm in the adulthood . Genotypes also vary from region to region and by ethnicity . In the U.S., genotypes A and D are often seen in Caucasians and African Americans, as opposed to B and C in Asian Americans. Genotypes C, especially C2, and D are known to have a greater association with hepatocarcinogenesis , possibly because they are more likely to be found in patients with more severe liver disease . Of note, genotype B has been shown in some studies to be associated with the development of HCC in young non-cirrhotic carriers of HBV.
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How Do You Get Hepatitis B
In the U.S., people usually get hepatitis B infection through sexual transmission or intravenous drug use. In other parts of the world where hepatitis B is more common, such as Southeast Asia, mother-to-child transmission at birth is the most common way people get infected. Unlike hepatitis A infection, hepatitis B has the potential to become a chronic infection that requires lifelong management.