Understanding Your Test Results
Understanding your hepatitis B blood tests can be confusing. It is important to talk to your health care provider so you understand your test results and your hepatitis B status. Are you infected? Protected? Or at risk? The Hepatitis B Panel of blood tests includes 3 tests and all three results must be known in order to confirm your status.
Below is a chart with the most common explanation of the test results, but unusual test results can occur. Please note that this chart is not intended as medical advice, so be sure to talk to your health care provider for a full explanation and obtain a printed copy of your test results. In some cases, a person could be referred to a liver specialist for further evaluation.
More Detailed Information About Hepatitis B Blood Tests
An acute hepatitis B infection follows a relatively long incubation period â from 60 to 150 days with an average of 90 days. It can take up to six months, however, for a person to get rid of the hepatitis B virus. And it can take up to six months for a hepatitis B blood test to show whether as person has recovered from an acute infection or has become chronically infected .
The following graphic from the U.S. Centers for Disease Control and Prevention represents the typical course of an acute hepatitis B infection from first exposure to recovery.
According to the CDC, a hepatitis B blood test result varies depending on whether the infection is a new acute infection or a chronic infection.
Lateral Flow Rapid Diagnostic Tests
Three HBV immunochromatographic RDT that have been prequalified by the World Health Organization include Determine HBsAg , VIKIA HBsAg and SD Bioline WB . These RDTs have met WHO ASSURED criteria and detect HBsAg and HBeAg in a single-use, disposable format . Evaluation of a rapid immunochromatographic test for simultaneous detection of HBsAg and HBeAg, in comparison with standard EIA, showed excellent accuracy, with sensitivity and specificity for HBsAg detection at 95 and 100%, respectively, although performance characteristics for HBeAg detection were decreased compared with the EIA method .
Several immunochromatographic lateral flow RDT have been tested and found suitable for HCV diagnosis. Mahajan et al. , compared three different RDT manufactured in India for detection of HCV antibody. They found moderate sensitivity and excellent specificity with HCV suspected cases within a Delhi liver clinic, with increased sensitivity among RNA positive patients . The InTec POC cassette has been evaluated in several HCV screening studies and displays good sensitivity and specificity for screening general and high-risk populations in Pakistan . Sensitivity of HCV RDT among HIV/HCV co-infected populations can be affected by HIV status. Hence, external validation of the RDT is needed prior to testing in such populations .
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Hepatitis B Rapid Test Kit
Hep B STI Home Self Test Kit.
Hepatitis B is an infectious disease caused by the Hepatitis B virus which affects the liver. It is a contagious STI spread by bodily fluids. It can cause both acute and chronic infections. Many people in Australia have no symptoms during infection. Some develop a rapid onset of sickness with Hep B Symptoms such as vomiting, yellow skin, feeling tired, dark urine and abdominal pain on the right-hand side. It may take 30 to 180 days for symptoms to begin. Cirrhosis and liver cancer may eventually develop in those infected. These complications can result in the death of 15 to 25% of those with chronic disease. About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Globally over 750,000 people die of hepatitis B each year. There are approx. 230,000 Australians living with Hepatitis B.
Hep B infection can be easily detected by testing at home with an STI Hep B self-test kit.
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Investigational Determine Hbsag 2 Test
The Determine HBsAg 2 test is an in vitro, visually read, qualitative, immunochromatographic assay for the detection of HBsAg in human serum, plasma, fingerstick whole blood or venous whole blood.
The Determine HBsAg 2 test consists of single-use test strips and a chase buffer bottle, both stored at room temperature and requires no maintenance. The assay requires 50µL specimen for a test, and the test result can be interpreted at 15minutes and no later than at 30minutes. Details of the test can be found in the package insert.
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What Does The Test Measure
At-home hepatitis B tests measure hepatitis B surface antigens . Hepatitis B surface antigens are proteins on the outside of the hepatitis B virus that trigger an immune system response to fight the infection.
Hepatitis B surface antigens can be detected as early as 2 or as late as 12 weeks after a person was exposed to HBV. In patients who recover from hepatitis B, HBsAg usually becomes undetectable within 4 to 6 months.
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TheHBsAg Test is a rapid visual immunoassay for the qualitative, presumptive detection of HBsAg in human serum or plasma specimens. This kit is intended to be used as an aid in the diagnosis of HBV infection.
Hepatitis B virus is the prototypic member of the hepadnaviruses. Hepatitis B surface antigen is located in the lipid envelope of this small DNA virus. During the replicative phase of the virus, this surface antigen is produced in excess and is detectable in the blood of the infected. The incubation period of HBV is 6 weeks to 6 months.
Rapid test cassette with desiccant. Disposable pipettes.
Store at 2 ~ 30 º C in the sealed pouch for 24 months. Keep away from direct sunlight, moisture and heat. DO NOT FREEZE
Bring tests, specimens, and/or controls to room temperature before use.
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How Do We Test For Hepatitis B
The FDA-approved hepatitis B virus test looks for surface antigens to determine if you have hepatitis B. . Surface antigens are the first signs of acute infection, but they are also present in chronic infections.
Finding a hepatitis B infection early is extremely beneficial for avoiding liver health complications.
If the HBV test returns a positive result, a second confirmation test is performed at no extra charge to ensure that you receive the most accurate results possible. The accuracy of laboratory testing is measured in terms of sensitivity and specificity. Our HBV test has an 88% sensitivity rate and a 99-100% specificity rate.
Specification Of Hepatitis B Surface Antigen Test
The LINEAR Hepatitis B Antigen Cassette Test detects HBSAG concentration greater than 2 ng/ml in human serum by the development of a colored line in the test region of the test device.
The LINEAR Hepatitis B Antigen Cassette Test uses an antibody that is highly specific for Hepatitis B Antigen in serum. A result of 99.5 % concordance to the ELISA test was determined by a clinical study of 1208 samples.
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Rapid Point Of Care Diagnostic Testing
LMIC may benefit from reappraisal of the testing algorithm used in high income countries, such that entry into care and treatment is initiated based on a combination of rapid and confirmatory testing to provide the most efficient, cost-effective, and accurate diagnoses . Significantly, the cost-effectiveness and utility of rapid tests for effective screening is not necessarily realized in high resource countries, dependent on infection prevalence and the rate of successful prevention and management of chronic infection . Well-recognized testing platforms for rapid diagnostic testing that will be discussed in this review include lateral flow devices , rapid, cartridge-based molecular marker detection devices, and dried blood spot collection to facilitate screening, diagnosis, and monitoring.
Who Should Get Hbv Tested
The following persons are exposed to the risk of HBV infection and is advised to take HBV test regularly: those having sex without taking protection sharing needles in drugs injection getting a tattoo or piercing with tools that are not disinfected properly sharing personal items such as razor and toothbrush.
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Hbsag Rapid Test Performance Using Reference Panels
The reference panel was composed of 393 individuals, 103 of which were HBsAg reactive , whereas 290 samples did not show HBsAg according to EIAs. The mean age of the patients was 40.32 years , and most were female . HBsAg was detected in 101, 98 and 96 of the samples, with sensitivities of 98.06, 95.15 and 93.20 % by Vikia® HBsAg, Imuno-Rápido HBsAg® and HBsAg Teste Rápido®, respectively .
Table 1 Accuracy metrics of three rapid tests compared to results of HBsAg One® and ETI-MAK-4®, enzyme immunoassays
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Faq About Hepatitis B Testing
The Hepatitis B Surface Antigen is a blood test that detects early signs of infection within the body. It is a safe and precise test that works by searching the bloodstream for traces of the virus. If you, or someone you know, feels they have contracted or had an encounter with Hepatitis B, we recommended testing as soon as possible. Early detection reduces the risk of the STD becoming chronic. If you arent sure what testing options are best for you, our professionals are only a phone call away. Theyll help you make an informed decision on proper testing options for you.
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Chronic Hepatitis B May Be Treated With:
1. Antiviral medications
Several antiviral medications, such as entecavir , tenofovir , lamivudine , adefovir , and telbivudine, are able to assist in the fight against the virus and decrease its capacity to cause damage to your liver.
2. Interferon injections
Interferon alfa-2b, also known as Intron A, is a synthetic form of the naturally occurring anti-infectious chemical known as interferon alfa-2. It is most commonly prescribed to young persons with hepatitis B who desire to avoid long-term treatment or to female patients who have recently finished a complete course of treatment and are considering becoming pregnant within the next several years.
3. Liver transplant
If your liver has sustained significant damage, getting a liver transplant may be one of your treatment options. The surgeon will remove your diseased liver and replace it with a new liver that has been donated during a liver transplant procedure.
Hepatitis B Surface Antigen Rapid
A blood test called hepatitis B surface antigen is used to see if someone has the hepatitis B virus. If it is discovered, along with specific antibodies, it indicates that the person has hepatitis B. If you have HBsAg in your blood, it means you are infected with the virus and can spread it to others through your blood or bodily fluids.
A Hepatitis B Surface Antigen Rapid helps to detect the infection with Hepatitis B virus and provides you with a clear picture of whatâs wrong with your body. You can secure some fantastic Hepatitis B Surface Antigen Rapid Delhi for a complete diagnosis of body check-up.
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Hbsag And Hbv Detection
Serum samples from the reference panel were tested for HBsAg markers using two commercial EIAs following the manufacturers instructions. Only samples with concordant results defined by both assays were included in the study. Serum samples from the field study were assayed for HBsAg detection using a commercial EIA . All HBsAg-reactive samples in the EIA were retested in duplicate. All serum samples were assayed for total antibodies directed against the total core antigen as well as anti-HBs using EIAs . Serum samples were also assayed for anti-HBc IgM, HBV e antigen and antibodies against HBeAg using commercial EIAs and ECLIAs when sufficient sample volume was available.
Study Selection And Characteristics
A total of 11,589 citations were identified, and 293 full-text articles examined which identified 40 studies meeting pre-defined criteria . Of the included studies, 33 compared RDTs and/or EIAs against an immunoassay reference standard, of which five focused on accuracy in HIV-positive individuals . Seven studies compared RDTs and/or EIAs against a NAT reference standard, of which 3 had data from HIV-positive patients . Studies were all either cross-sectional or case-control, predominantly in the laboratory setting, and performed in a broad range of populations, including healthy volunteers, blood donors, pregnant women, incarcerated adults, HIV and hepatitis patient cohorts with confirmed HBV infection. The prevalence of HBV ranged from 1.9 to 84% in populations tested. A mixture of serum, plasma and whole blood was used for RDTs, while studies of EIAs were performed on serum or plasma samples. Study characteristics are presented in Tables , and .
Fig. 1
Three studies had data from 442 HIV-positive patients in Uganda and South Africa, with pooled sensitivity and specificity of 57.9% and 95.8% , respectively. The corresponding pooled sensitivity and specificity for the 202 HIV-negative patients across two of these studies were 83.3% and 85.7% , respectively .
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Hepatitis B Blood Tests
The Hepatitis B Panel of Blood Tests
Only one sample of blood is needed for a hepatitis B blood test, but the Hepatitis B Panel includes three parts. All three test results are needed to fully understand whether a person is infected or not. Below is an explanation of the 3-part Hepatitis B Panel of blood test results.
When Should We Take A Quick Test For Hepatitis B
- Increase in ALT and AST levels
- Clinical signs of acute or chronic viral hepatitis, chronic diseases of the liver and bile ducts
- Examination of the disease in the family / team
- Preparation for vaccination
- Examination of patients undergoing frequent parenteral manipulations
- Preparation for hospitalization, surgery
- Pregnant women and preparations for pregnancy
- Preventive screening of donors, people at risk
- Unprotected sex, frequent change of sexual partners
- Intravenous drug users.
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Data Extraction And Quality Assessment
Two authors independently extracted data and reached agreement on the following variables: study author and year study location and design specimens tested eligibility criteria index test and reference standard, including manufacturer raw cell numbers HIV co-infection sources of funding and reported conflict of interest.
Study quality was evaluated using the QUADAS-2 tool , which evaluates risk of bias and applicability concerns .
Does The Hepatitis B Test Use Urine Or Blood
The Hepatitis B test facility conducts on blood donated by the patient.
What Should You Do To Get Ready For The Test?
There is no need to fast or prepare simply visit the lab of your choice as soon as possible & get tested for Hepatitis B.
Who Should Be Tested For Hepatitis B?
People who have hepatitis B frequently have no symptoms and are unaware that they are infected. If you do have symptoms, they might include extreme exhaustion, lower abdominal tenderness or pain, appetite loss, nausea, vomiting, joint pain, headache, fever, and hives. Six weeks to six months after the infection has entered the body, these symptoms may start to manifest.
When Is The Ideal Time To Have the Testing Done?
Highly contagious and spreadable through the bodily fluids of an infected person, hepatitis B is typically spread through sexual contact, the sharing of needles, or the use of intravenous drugs.
Although the test can identify an HBV infection as soon as 3 weeks after exposure, our clinicians advise waiting 6 weeks before testing to ensure the most accurate results.
If you have a few of these symptoms or have come into contact with someone who has a chronic HBV infection, you should think about getting tested. Hepatitis B testing should be a regular part of your STD screening regimen.
What Will The Result Reveal?
Is Hepatitis B Curable?
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