Friday, November 25, 2022

What Organ Does Hepatitis Affect

What Are The Symptoms Of Hepatitis A

Viral Hepatitis – How Does Hepatitis Affect The Liver? Acute vs Chronic Hepatitis

Some people have symptoms 2 to 7 weeks after they come in contact with the virus.3 People with hepatitis A typically get better without treatment after a few weeks. In some cases, symptoms can last up to 6 months. These symptoms may include

Some people infected with hepatitis A have no symptoms, including many children younger than age 6.3 Older children and adults are more likely to have symptoms.

How Does Hepatitis C Virus Affect Your Central Nervous System

As discussed above, HCV can damage many other parts of the body. HCV causes damage to the CNS as well. This happens because the liver is unable to filter out the toxins from the bloodstream. Some of the symptoms of damage to the CNS include:

  • Sweet or musty breath
  • Difficulty managing small motor skills
  • Forgetfulness or state of confusion
  • Poor concentration

In some extremely severe cases, HCV can also cause a person to slip into a coma.

How Is Hepatitis B Spread

You can become infected with hepatitis B through exposure to blood, semen and other bodily fluids of an infected person. You can get the infection by:

  • Having unprotected sex.
  • Sharing or using dirty needles for drug use, tattoos or piercing.
  • Sharing everyday items that may contain body fluids, including razors, toothbrushes, jewelry for piercings and nail clippers.
  • Being treated medically by someone who does not use sterile instruments.
  • Being bitten by someone with the infection.
  • Being born to a pregnant woman with the infection.

Hepatitis B is not spread by:

  • Kissing on the cheek or lips.
  • Coughing or sneezing.
  • Hugging, shaking hands or holding hands.
  • Eating food that someone with the infection has prepared.
  • Breastfeeding.

Also Check: Who Should Get Hepatitis B Vaccine

Who Are Hepatitis B Carriers

Hepatitis B carriers are people who have the hepatitis B virus in their blood, even though they dont feel sick. Between 6% and 10% of those people whove been infected with the virus will become carriers and can infect others without knowing it. There are over 250 million people in the world who are carriers of HBV, with about 10% to 15% of the total located in India. Children are at the highest risk of becoming carriers. About 9 in 10 babies infected at birth become HBV carriers, and about half of children who are infected between birth and age 5 carry the virus. A blood test can tell you if you are a hepatitis B carrier.

Prevent Infection After Contact With The Virus

Hepatitis

If you think you have been in contact with the hepatitis B virus, see your doctor right away. Doctors typically recommend a dose of the hepatitis B vaccine to prevent infection. In some cases, doctors may also recommend a medicine called hepatitis B immune globulin to help prevent infection. You must get the vaccine dose and, if needed, HBIG shortly after coming into contact with the virus, preferably within 24 hours.

Also Check: Hepatitis A Vaccine Side Effects Baby

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When To See A Healthcare Provider

If you develop any of the symptoms of chronic hepatitis, liver damage, or liver cancer, see your healthcare provider. It takes only a blood test to detect the presence of a hepatitis virus in your body .

A blood test also can determine which hepatitis virus you’re infected with, which will determine what your treatment should be .

Hepatitis Affects What Organ Of The Body

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How Is Viral Hepatitis Spread

Hepatitis A and hepatitis E usually spread through contact with food or water that was contaminated with an infected person’s stool. You can also get hepatitis E by eating undercooked pork, deer, or shellfish.

Hepatitis B, hepatitis C, and hepatitis D spread through contact with the blood of someone who has the disease. Hepatitis B and D may also spread through contact with other body fluids. This can happen in many ways, such as sharing drug needles or having unprotected sex.

What Are The Symptoms And Signs Of Viral Hepatitis

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The period of time between exposure to hepatitis and the onset of the illness is called the incubation period. The incubation period varies depending on the specific hepatitis virus. Hepatitis A virus has an incubation period of about 15 to 45 days Hepatitis B virus from 45 to 160 days, and Hepatitis C virus from about 2 weeks to 6 months.

Many patients infected with HAV, HBV, and HCV have few or no symptoms of illness. For those who do develop symptoms of viral hepatitis, the most common are flu-like symptoms including:

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Chronic Hepatitis B Symptoms

Most patients with chronic hepatitis B are asymptomatic unless their disease progresses. Others might have nonspecific symptoms, such as fatigue.

Some patients experience worsening of the infection and develop signs and symptoms similar to acute hepatitis.

If patients with chronic hepatitis B progress to cirrhosis they will develop signs and symptoms of liver failure, including:

  • Jaundice
  • Ascites
  • Peripheral edema
  • Encephalopathy
  • Hepatocellular carcinoma

How Are Hepatitis B And C Diagnosed

Hepatitis B is diagnosed by a series of blood tests. The test may show an ongoing infection or antibodies that indicate that the patient is protected against hepatitis B. In patients who have a positive screening test that suggests the possibility of ongoing infection, further testing is done to determine the levels of the virus in the bloodstream.

Hepatitis C is diagnosed via a blood test called a Hepatitis C Antibody Test. A positive result means that hepatitis C antibodies are present in the blood. But a positive antibody test doesnt necessarily mean a person has hepatitis C. A further blood test is needed to confirm the diagnosis. This second blood test quantifies the amount of the virus or the viral load in the liver and the bloodstream.

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How Do Doctors Treat Hepatitis A

Treatment includes resting, drinking plenty of liquids, and eating healthy foods to help relieve symptoms. Your doctor may also suggest medicines to help relieve symptoms.

Talk with your doctor before taking any prescription or over-the-counter medicines, vitamins or other dietary supplements, or complementary or alternative medicinesany of these could damage your liver. You should avoid alcohol until your doctor tells you that you have completely recovered from hepatitis A.

See your doctor regularly to make sure your body has fully recovered. If you have symptoms for longer than 6 months, see your doctor again.

What Are Hepatitis B And Hepatitis C

How Does Hepatitis C Affect Non

Although hep A is a short-term illness that goes away completely, hepatitis B and hepatitis C can turn into serious long-term illnesses for some people. Teens and young adults are most at risk for getting these two viruses.

Hep B and C get passed from person to person the same ways that HIV does through direct contact with infected body fluids. Hepatitis B and C are even more easily passed in fluids and needles than HIV. This can happen through sexual contact and by sharing needles that have been contaminated with infected blood. Even when infected people don’t have any symptoms, they can still pass the disease on to others.

Sometimes mothers with hep B or C pass the virus along to their babies when they’re born. Hep B and C also can get passed in ways you might not expect such as getting a manicure or pedicure with unsterilized nail clippers or other dirty instruments. Getting a tattoo, if dirty needles are used, is another way someone can get hep B or C.

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Willowbrook State School Experiments

A New York University researcher named Saul Krugman continued this research into the 1950s and 1960s, most infamously with his experiments on mentally disabled children at the Willowbrook State School in New York, a crowded urban facility where hepatitis infections were highly endemic to the student body. Krugman injected students with gamma globulin, a type of antibody. After observing the temporary protection against infection this antibody provided, he then tried injected live hepatitis virus into students. Krugman also controversially took feces from infected students, blended it into milkshakes, and fed it to newly admitted children.

Treatment And Medication For Hepatitis C

If you have acute hepatitis C, there is no recommended treatment. If your hepatitis C turns into a chronic hepatitis C infection, there are several medications available.

Interferon, peginterferon, and ribavirin used to be the main treatments for hepatitis C. They can have side effects like fatigue, flu-like symptoms, anemia, skin rash, mild anxiety, depression, nausea, and diarrhea.

Now youâre more likely to get one of these medications:

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What Causes Hepatitis B

The hepatitis B virus causes hepatitis B. The hepatitis B virus spreads through contact with an infected persons blood, semen, or other body fluids. Contact can occur by

  • being born to a mother with hepatitis B
  • having unprotected sex with an infected person
  • sharing drug needles or other drug materials with an infected person
  • getting an accidental stick with a needle that was used on an infected person
  • being tattooed or pierced with tools that were used on an infected person and werent properly sterilized, or cleaned in a way that destroys all viruses and other microbes
  • having contact with the blood or open sores of an infected person
  • using an infected persons razor, toothbrush, or nail clippers

You cant get hepatitis B from

  • being coughed on or sneezed on by an infected person
  • drinking unclean water or untreated water that has not been boiled
  • eating food that is unclean or has not been properly cooked
  • hugging an infected person
  • shaking hands or holding hands with an infected person
  • sharing spoons, forks, and other eating utensils
  • sitting next to an infected person

Mothers who have hepatitis B can safely breastfeed their babies. If a baby receives hepatitis B immune globulin and starts receiving the hepatitis B vaccine to prevent hepatitis B infection shortly after birth, hepatitis B is unlikely to spread from mother to child through breastfeeding.15

The Most Common Conditions Associated With Hepatitis C:

Mayo Clinic Minute: ABCs of hepatitis

Cryoglobulinemia It is the most common condition associated with Hepatitis C. It normally develops due to the presence of abnormal proteins in the blood called cryoglobulins.

These abnormal proteins originate from the stimulation of lymphocytes by the Hepatitis C virus and can deposit in the small and medium-sized blood vessels.

Then they restrict the blood flow and leads to the infection of blood vessels in the tissues of the body, including the skin, joints and kidneys .

Canities : It is a health condition where the affected person experiences premature graying of the hair.

B-cell non-Hodgkins lymphoma This is a cancer of the lymphoid tissues associated with the Hepatitis C virus.

It can be low-grade or high-grade . Its usually develops due to the excessive Hepatitis C virus stimulation of B-lymphocytes, leading to the abnormal growth of the lymphocytes.

Lichen planus It is a skin condition associated with Hepatitis C Virus. This disorder usually appears as shiny, small-elevated bumps on flexor surfaces . The condition usually develops due to the reproduction of HCV in epithelial cells.

Diabetes mellitus This is a very common metabolic disorder that is associated with Hepatitis C Virus. It usually develops when the body is unable to produce insulin, the hormone that controls the sugar levels in the blood.

The other conditions associated with Hepatitis C infection are Thyroid Disease, Kidney Disease , Peripheral Neuropathy, and Porphyria Cutanea Tarda .

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How Is Viral Hepatitis Diagnosed

Diagnosis of viral hepatitis is based on symptoms and physical findings as well as blood tests for liver enzymes, viral antibodies, and viral genetic materials.

Symptoms and physical findings

Diagnosis of acute viral hepatitis often is easy, but the diagnosis of chronic hepatitis can be difficult. When a patient reports symptoms of fatigue, nausea, abdominal pain, darkening of urine, and then develops jaundice, the diagnosis of acute viral hepatitis is likely and can be confirmed by blood tests. On the other hand, patients with chronic hepatitis due to HBV and HCV often have no symptoms or only mild nonspecific symptoms such as chronic fatigue. Typically, these patients do not have jaundice until the liver damage is far advanced. Therefore, these patients can remain undiagnosed for years to decades.

Blood tests

There are three types of blood tests for evaluating patients with hepatitis: liver enzymes, antibodies to the hepatitis viruses, and viral proteins or genetic material .

Liver enzymes: Among the most sensitive and widely used blood tests for evaluating patients with hepatitis are liver enzymes, called aminotransferases. They include aspartate aminotransferase and alanine aminotransferase . These enzymes normally are contained within liver cells. If the liver is injured , the liver cells spill the enzymes into the blood, raising the enzyme levels in the blood and signaling that the liver is damaged.

Examples of tests for viral antibodies are:

What Are The Symptoms Of The Hepatitis A Virus

Low energy is the most common symptom of HAV. Other symptoms include fever, tiredness, loss of appetite, nausea, headache, itchy skin, muscle soreness, pain near the liver, and jaundice .

Symptoms of HAV can occur two to seven weeks after infection and are often mild. Children may not have any symptoms. Symptoms usually go away within two months. If you think you have HAV, it is important to see a doctor symptoms of HAV are similar to other more serious liver diseases.

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Treating Hepatitis C Matters

When you see your doctor and start treatment for a chronic hep C infection, you can prevent these problems, improve them, or keep them from getting worse. New drugs can clear the virus from your body in a few months with fewer side effects than older medicines. If thereâs no virus in your blood 3 months after treatment, youâre considered cured.

Getting rid of the infection protects others, too. Hepatitis C spreads through blood-to-blood contact. You could infect a loved one if you accidentally use their toothbrush or cut yourself and donât clean up the blood properly. People who get hep C treatment greatly lower the odds that they will pass the virus to someone else.

If you arenât sure if you have hepatitis C, talk to your doctor to see if you should get tested. Learn why you should get tested for hepatitis C.

How Are Hepatitis B And C Treated

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Hepatitis B: Not all patients with chronic hepatitis B infection require treatment. At Yale Medicine, specialists decide on an individual basis whether a patient is an appropriate candidate for treatment. Generally, patients require treatment when their hepatitis B virus level is high, and when laboratory tests demonstrate significant inflammation or injury to the liver.

There are currently seven approved drugs for hepatitis B, two of which are considered to be first-line treatments. These drugs are oral pills taken once daily, and while they’re very effective at suppressing the virus to very low or undetectable levels over the long term, they are not considered curative.

Therefore, the goal of treatment is to control the virus long-term and decrease the risk of hepatitis B related complications such as cirrhosis and liver cancer.

Hepatitis C: For the greater part of the last 20 years, treatment of hepatitis C required the use of a chemotherapy-like injection drug called interferon, which has been associated with serious side effects and a low cure rate. Fortunately, advances in hepatitis C treatments within the last three years now allow for the use of oral medications that are significant improvements in terms of safety and effectiveness.

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Hepatitis B In The United States

In the United States, about 862,000 people have chronic hepatitis B.6 Asian Americans and African Americans have higher rates of chronic hepatitis B than other U.S. racial and ethnic groups.10 Researchers estimate that about half of the people living with chronic hepatitis B in the United States are Asian Americans and Pacific Islanders.11 Chronic hepatitis B is also more common among people born in other countries than among those born in the United States.7

The hepatitis B vaccine has been available since the 1980s and, in 1991, doctors began recommending that children in the United States receive the hepatitis B vaccine. The annual rate of acute hepatitis B infections went down 88.5 percent between 1982 and 2015.12 In 2017, the annual number of hepatitis B infections rose in some states.13 Experts think the rise was related to increases in injection drug use. Injection drug use increases the risk of hepatitis B infection.

How Do You Know If You Have Hepatitis C

A simple blood test can easily identify the presence of HCV antibodies in your bloodstream. If these antibodies are present, then it means that you have been exposed to the virus in recent times. If the first blood test confirms the presence of HCV antibodies, then your doctor will schedule another blood test to confirm that you have an HCV infection.

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Treating Hepatitis C Can Help Alleviate Skin Conditions

The good news is that there have been great advancements in the treatment of chronic hepatitis C using direct-acting antiviral medications, which reduce the viral load significantly enough to cure the infection.

They involve taking pills once a day for eight to 12 weeks, with cure rates above 95 percent, says Kuo. Unlike past treatments for hepatitis C, direct-acting antivirals are also safe and have minimal side effects. Once the hepatitis C is treated, all related skin issues should clear as well.

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